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#46
15.06.2011, 23:42
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- контактная аллергия у медиков(цефалоспорины)
[Ссылки доступны только зарегистрированным пользователям ] Occupational contact allergy to cephalosporins [Ссылки доступны только зарегистрированным пользователям ] - кальциноз кожи в 2-х частях [Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] Efficacy of tacrolimus 0.1% ointment in cutaneous lupus erythematosus: A multicenter, randomized, double-blind, vehicle-controlled trial [Ссылки доступны только зарегистрированным пользователям ] Conclusion Explorative subgroup analyses revealed that topical application of tacrolimus 0.1% ointment may provide at least temporary benefit, especially in acute, edematous, non-hyperkeratotic lesions of CLE patients, suggesting that calcineurin inhibitors may represent an alternative treatment for the various disease subtypes. Classification of hand eczema: clinical and aetiological types. Based on the guideline of the Danish Contact Dermatitis Group [Ссылки доступны только зарегистрированным пользователям ] 
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#47
28.06.2011, 02:28
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- подробная статья о физиологических изменениях/дерматозах во время беременности:
Physiologic changes and dermatoses of pregnancy [Ссылки доступны только зарегистрированным пользователям ] - АД/экземы: Atopic dermatitis: a disease of altered skin barrier and immune dysregulation [Ссылки доступны только зарегистрированным пользователям ] Contact sensitization pattern in 172 atopic subjects [Ссылки доступны только зарегистрированным пользователям ] Egg allergy in patients over 14 years old suffering from atopic eczema [Ссылки доступны только зарегистрированным пользователям ] Conclusion Egg allergy may play an important role in the worsening of atopic eczema acting as a triggering–exacerbating factor in a minority of patients. The diagnostic work-up may comprise the challenge tests to confirm the food allergy to egg. - нет данных за то, что есть смысл при прекращении ГВ для профилактики аллергозаболеваний использовать частично-гидролиз. смеси Effect of a partially hydrolyzed whey infant formula at weaning on risk of allergic disease in high-risk children: A*randomized controlled trial [Ссылки доступны только зарегистрированным пользователям ] Conclusion Despite current dietary guidelines, we found no evidence to support recommending the use of pHWF at weaning for the prevention of allergic disease in high-risk infants. Disposable nappies for preventing napkin dermatitis in infants: a summarised Cochrane review [Ссылки доступны только зарегистрированным пользователям ] Authors’ conclusions There is not enough evidence from good quality randomised controlled trials to support or refute the use and type of disposable napkins for the prevention of napkin dermatitis in infants. - псориаз: - алкоголь и псориаз "несовместимы", был средней степени тяжести-может быть в итоге более тяжелой: Alcohol misuse high in moderate to severe psoriasis patients [Ссылки доступны только зарегистрированным пользователям ] The team notes: "Based on our results, we propose that all patients with moderate to severe psoriasis should be screened with the AUDIT questionnaire." [Ссылки доступны только зарегистрированным пользователям ] Conclusion Alcohol misuse is common in patients with moderate to severe psoriasis. Screening with the AUDIT questionnaire and CDT may allow the identification of patients who are misusing alcohol and allow appropriate intervention. Stress and quality of life in psoriasis: an update [Ссылки доступны только зарегистрированным пользователям ] - разное: Approach to reticulate hyperpigmentation [Ссылки доступны только зарегистрированным пользователям ] Low-dose UVA1 phototherapy for scleroderma: what benefit can we expect? [Ссылки доступны только зарегистрированным пользователям ] Conclusions Our experience allows us to conclude that low-dose UVA1 phototherapy is a well tolerated option, with excellent results mainly in patients with morphea. This treatment is a valuable contribution to these patients, given the limited therapeutic options available. Acroangiodermatitis in a below-knee amputation stump [Ссылки доступны только зарегистрированным пользователям ] Histiocytoid Sweet syndrome [Ссылки доступны только зарегистрированным пользователям ] Tender erythematous papules on the elbows, buttocks and knees [Ссылки доступны только зарегистрированным пользователям ] Interventions for Old World cutaneous leishmaniasis: a summarised Cochrane review [Ссылки доступны только зарегистрированным пользователям ] - хороший шампунь, да не наш("клобекс", "clobex", некоторым пациентам с псориазом волос. части головы хотя бы, удается заказать) Efficacious and safe management of moderate to severe scalp seborrhoeic dermatitis using clobetasol propionate shampoo 0·05% combined with ketoconazole shampoo 2%: a randomized, controlled study [Ссылки доступны только зарегистрированным пользователям ] Conclusions The combination therapy of twice-weekly CP alternating with twice-weekly KC provided significantly greater efficacy than KC alone and a sustained effect in the treatment of moderate to severe scalp seborrhoeic dermatitis. Clinical and healthcare status of patients with neurofibromatosis type 1 [Ссылки доступны только зарегистрированным пользователям ] Clinical features of idiopathic guttate hypomelanosis in 646 subjects and association with other aspects of photoaging [Ссылки доступны только зарегистрированным пользователям ] Conclusions It is very likely that IGH is a phenomenon associated with the skin’s normal aging process and repeated microtrauma to skin. - неплохая статья по тяжелым лекарственным реакциям: Severe adverse cutaneous drug eruptions: epidemiological and clinical features [Ссылки доступны только зарегистрированным пользователям ] Our study showed the importance of a thorough clinical and biological examination in the management of patients with specific forms of drug eruption, in search of severity makers enabling the detection of visceral involvement that require specific treatment. Besides, any prescription has to be justified because it could be responsible for a severe life-threatening ACDR. - пузырные: Direct immunofluorescence of plucked hair for evaluation of immunologic remission in pemphigus vulgaris [Ссылки доступны только зарегистрированным пользователям ] Conclusions The sensitivity of hair DIF was not high enough to allow us to suggest it as a substitute for conventional DIF. On the other hand, one cannot disregard positive cases of hair DIF in the setting of negative biopsy DIF. As hair plucking is less invasive than biopsy, the following approach could be suggested: hair DIF may be repeated in patients in clinical remission until negative; then conventional DIF should be performed, too. The physician can decide to stop treatment only when DIF assays on both substrates are negative. Drug-induced pemphigus [Ссылки доступны только зарегистрированным пользователям ] Ultrastructure and molecular pathogenesis of epidermolysis bullosa [Ссылки доступны только зарегистрированным пользователям ] - онкология Dermoscopy of Pigmented Lesions of the Mucosa and the Mucocutaneous Junction [Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] Conclusion* The combination of blue, gray, or white color with structureless zones are the strongest indicators when differentiating between benign and malignant mucosal lesions in dermoscopy. What’s new in skin cancer? An analysis of guidelines and systematic reviews published in 2008–2009 [Ссылки доступны только зарегистрированным пользователям ] Imiquimod 5% cream for the treatment of nasal lesion of metastatic renal cell carcinoma [Ссылки доступны только зарегистрированным пользователям ] Consequently, imiquimod may be safely used to treat not only primary skin tumors, but also skin metastases, which is a vascular abundant tumor like RCC. The present authors also believe this imiquimod cream may become a therapeutic option for metastatic skin lesions, especially for facial lesions for which total resection cannot be performed for cosmetic reasons. Clinical and dermoscopic features of 88 scalp naevi in 39 children [Ссылки доступны только зарегистрированным пользователям ]
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#49
29.07.2011, 23:00
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разное
New horizons for cutaneous microbiology: the role of biofilms in dermatological disease
[Ссылки доступны только зарегистрированным пользователям ] Cardiomyopathy with Alopecia and Palmoplantar Keratoderma (CAPK) is caused by a JUP mutation [Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] the*Indian Journal of Dermatology, Venereology and Leprology Year*: 2011* |**Volume*: 77* |**Issue*: 4 Lichenoid tissue reaction/interface dermatitis: Recognition, classification, etiology, and clinicopathological overtones [Ссылки доступны только зарегистрированным пользователям ] Epidermolysis bullosa: Where do we stand? [Ссылки доступны только зарегистрированным пользователям ] Bullous pemphigoid [Ссылки доступны только зарегистрированным пользователям ] Evidence-based treatments for pemphigus vulgaris, pemphigus foliaceus, and bullous pemphigoid: A systematic review [Ссылки доступны только зарегистрированным пользователям ] Dermatoses in the first 72 h of life: A clinical and statistical survey [Ссылки доступны только зарегистрированным пользователям ] Chronic urticaria in patients with autoimmune thyroiditis: Significance of severity of thyroid gland inflammation [Ссылки доступны только зарегистрированным пользователям ] Spectrum of seborrheic keratoses in south Indians: A clinical and dermoscopic study [Ссылки доступны только зарегистрированным пользователям ] Primary focal hyperhidrosis: current treatment options and a step-by-step approach [Ссылки доступны только зарегистрированным пользователям ] Hyperhidrosis (excessive sweating) can be local, regional or general. Table*4.* Current surgical and non-surgical treatment options in a step-by-step approach for the four most frequent forms of primary focal hyperhidrosis (axillary, palmar, plantar, craniofacial hyperhidrosis) Acitretin Revisited [Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] Conclusion The use of acitretin over the last 20 years has proven to be an effective treatment and adjunct in a number of dermatological conditions. A thorough understanding of the drug, its efficacy, and potential side-effects is important for yielding a beneficial therapeutic outcome for patients. Evidence-based (S3) guideline on topical corticosteroids in pregnancy[Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] Women with skin conditions may need topical corticosteroids during pregnancy. However, little is known about the effects of topical corticosteroids on the fetus. Short and medium-term efficacy of specific hydrotherapy in inherited ichthyosis [Ссылки доступны только зарегистрированным пользователям ] Conclusion: A 3-week treatment at Avene hydrotherapy Centre provided significant and persisting improvement of QoL and clinical symptoms of patients with inherited ichthyoses. Pellagra: A Clinical, Histopathological, and Epidemiological Study of 7 Cases. [Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] CONCLUSIONS: Pellagra should be ruled out in patients with lesions on sun-exposed areas. Predisposing factors for pellagra should be assessed along with the social situation of patients and the presence of digestive or neurological abnormalities. Successful treatment of disseminated superficial actinic porokeratosis with calcipotriol [Ссылки доступны только зарегистрированным пользователям ] Idiopathic scrotal calcinosis: report of two cases and review of literature [Ссылки доступны только зарегистрированным пользователям ] Contagious Itch in Humans [Ссылки доступны только зарегистрированным пользователям ] Conclusions Human susceptibility to develop itch when exposed to visual cues is confirmed; it appears to be amplified in patients with AD. These findings suggest that interpersonal social cues can dramatically alter the subjective sensory experience of itch. Pyoderma gangrenosum, acne, and suppurative hidradenitis (PASH)–a new autoinflammatory syndrome distinct from PAPA syndrome [Ссылки доступны только зарегистрированным пользователям ] Conclusions The clinical triad of pyoderma gangrenosum, acne, and suppurative hidradenitis represents a new disease entity within the spectrum of autoinflammatory syndromes, similar to PAPA and aseptic abscesses syndrome. For this disease, we propose the acronym “PASH” syndrome. PASH syndrome may respond to IL-1? blockade. Question: Can you identify this condition? [Ссылки доступны только зарегистрированным пользователям ] The oral and skin pathergy test [Ссылки доступны только зарегистрированным пользователям ] Conditions with positive pathergy phenomenon: Behcet's disease [40] Pyoderma gangrenosum (PG): The pathergy test positivity at a rate of 25% has been reported in the literature in PG patients. [41] Aggressive surgical debridement or skin grafting is discouraged in these patients because of the risk of a pathergic response. Interferon alpha-treated chronic myeloid leukemia patients [42] Sweets syndrome [43],[44] Eosinophilic pustular folliculitis [45] Inflammatory bowel disease [46] Healthy individuals [47] Rarely in spondyloarthropathies Chronic urticaria in patients with autoimmune thyroiditis: Significance of severity of thyroid gland inflammation [Ссылки доступны только зарегистрированным пользователям ] Oxalosis Involving the Skin [Ссылки доступны только зарегистрированным пользователям ] CONCLUSIONS: This case highlights the variability of clinical presentations in primary hyperoxaluria and that the disease can be diagnosed in adulthood. In addition, this case demonstrates that hyperoxaluria should be included in the differential diagnosis of calciphylaxis and nephrogenic systemic fibrosis. A Prospective Randomized Controlled Trial Indicates That Sunscreen Use Reduced the Risk of Developing Melanoma [Ссылки доступны только зарегистрированным пользователям ] Identification of Ketoconazole as an AhR-Nrf2 Activator in Cultured Human Keratinocytes: The Basis of Its Anti-Inflammatory Effect [Ссылки доступны только зарегистрированным пользователям ] Handling Botulinum Toxins: An Updated Literature Review [Ссылки доступны только зарегистрированным пользователям ] Hemangiomas Erased With Propranolol [Ссылки доступны только зарегистрированным пользователям ] Venous ulcer review [Ссылки доступны только зарегистрированным пользователям ] Thrombophilia mimicking necrotizing fasciitis in a pregnant woman [Ссылки доступны только зарегистрированным пользователям ] Lyngbya dermatitis (toxic seaweed dermatitis) [Ссылки доступны только зарегистрированным пользователям ]
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#50
29.07.2011, 23:10
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Vitamin D, Calcium Combo May Halve Melanoma Risk in Some Women
[Ссылки доступны только зарегистрированным пользователям ] Conclusion Vitamin D supplementation at a relatively low dose plus calcium did not reduce the overall incidence of NMSC or melanoma. However, in women with history of NMSC, CaD supplementation reduced melanoma risk, suggesting a potential role for calcium and vitamin D supplements in this high-risk group. Results from this post hoc subgroup analysis should be interpreted with caution but warrant additional investigation. [Ссылки доступны только зарегистрированным пользователям ] "More studies need to be done, because we want to make sure these results are true in other communities," Tang said. The report was published in the June 27 online edition of the Journal of Clinical Oncology. [Ссылки доступны только зарегистрированным пользователям ] Calcium Plus Vitamin D Not Effective for Skin Cancer, But... [Ссылки доступны только зарегистрированным пользователям ] Intralesional Infusion of Methotrexate as Neoadjuvant Therapy Improves the Cosmetic and Functional Results of Surgery to Treat Keratoacanthoma: Results of a Randomized Trial. [Ссылки доступны только зарегистрированным пользователям ] CONCLUSIONS: Neoadjuvant intralesional methotrexate is well tolerated and reduces the need for aggressive surgery in elderly patients with keratoacanthoma measuring more than 1.5cm on the face or extremities. In vivo confocal microscopy for detection and grading of dysplastic nevi: A pilot study [Ссылки доступны только зарегистрированным пользователям ] Conclusion The possibility to detect dysplastic nevi in*vivo may lead to an appropriate management decision. Spectrum of seborrheic keratoses in south Indians: A clinical and dermoscopic study [Ссылки доступны только зарегистрированным пользователям ] Guideline Melanocytic nevi [Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] Treatment of Squamous Cell Carcinoma In Situ: A Review [Ссылки доступны только зарегистрированным пользователям ] Systemic treatment of locally-advanced, nonmetastatic cutaneous squamous cell carcinoma: a review of the literature [Ссылки доступны только зарегистрированным пользователям ] Safety, efficacy, and patient acceptability of imiquimod for topical treatment of actinic keratoses [Ссылки доступны только зарегистрированным пользователям ] Current and emerging treatment strategies for the treatment of actinic keratosis [Ссылки доступны только зарегистрированным пользователям ] Dermoscopy of scalp tumours: a multi-centre study conducted by the international dermoscopy society [Ссылки доступны только зарегистрированным пользователям ] New or unusual dermatopathology tumors: a review [Ссылки доступны только зарегистрированным пользователям ] Isolated distal cutaneous thrombosis: An unusual presentation and an interesting etiology [Ссылки доступны только зарегистрированным пользователям ] Generalized eruptive histiocytosis mimicking leprosy [Ссылки доступны только зарегистрированным пользователям ] Ectodermal dysplasia-skin fragility syndrome [Ссылки доступны только зарегистрированным пользователям ] Vancomycin-induced linear IgA bullous dermatosis mimicking toxic epidermal necrolysis [Ссылки доступны только зарегистрированным пользователям ] Systemic (allergic) contact dermatitis to diclofenac [Ссылки доступны только зарегистрированным пользователям ] Laugier-Hunziker syndrome [Ссылки доступны только зарегистрированным пользователям ] "Paradoxical" adverse effects caused by anti-tumor necrosis factor-alpha biological drugs: Appearance of psoriasis in a patient treated with infliximab for rheumatoid arthritis [Ссылки доступны только зарегистрированным пользователям ] Spontaneous regression of a congenital melanocytic nevus [Ссылки доступны только зарегистрированным пользователям ] Epidemiological trends in contact dermatitis to hair dye: Comparing para-phenylenediamine positivity after a decade long interval [Ссылки доступны только зарегистрированным пользователям ] Retrospective study of spectrum of cutaneous lymphoma presenting to dermatology [Ссылки доступны только зарегистрированным пользователям ] Perforating lichen planus [Ссылки доступны только зарегистрированным пользователям ] Response to Antimalarial Agents in Cutaneous Lupus Erythematosus [Ссылки доступны только зарегистрированным пользователям ] Conclusions* The use of quinacrine with hydroxychloroquine is associated with response in patients for whom hydroxychloroquine monotherapy fails. Further reduction in disease activity can be associated with continuation of treatment with antimalarial agents. Acute Generalized Exanthematous Pustulosis Simulating Toxic Epidermal Necrolysis [Ссылки доступны только зарегистрированным пользователям ] Conclusions* Because overlap exists, AGEP should be considered in the differential diagnosis of widespread blistering and erosive conditions. A greater understanding of how to differentiate AGEP and TEN can lead to quicker diagnosis as well as more effective case management and treatment. Pemphigus and pregnancy: A 23-year experience [Ссылки доступны только зарегистрированным пользователям ]
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#51
29.07.2011, 23:16
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Flutamide versus a cyproterone acetate-ethinyl estradiol combination in moderate acne: a pilot randomized clinical trial
[Ссылки доступны только зарегистрированным пользователям ] Conclusion: Flutamide appears to be more effective than a cyproterone-estradiol combination in some aspects of acne treatment, but this requires confirmation in a larger trial. (статью можно скачать полностью) Management strategies for acne vulgaris [Ссылки доступны только зарегистрированным пользователям ] Retinoid plus antimicrobial combination treatments for acne [Ссылки доступны только зарегистрированным пользователям ] Conclusions: Combination medications have superior efficacy and adherence, and have a similar tolerability profile compared with monotherapy of its components. Several studies have found antibiotic-containing combination products with a retinoid effective for acne. The use of antibiotic-containing combination medications for acne can lead to bacterial resistance. Due to this potential for bacterial resistance, benzoyl peroxide treatments are also recommended in combination with a retinoid. Rosacea fulminans in pregnancy: successful treatment with azithromycin [Ссылки доступны только зарегистрированным пользователям ] Laser resurfacing for facial acne scars: a summarised cochrane review [Ссылки доступны только зарегистрированным пользователям ] Main results No randomised controlled trials where laser treatment was compared to either placebo or a different type of laser were found. Most of the 27 studies uncovered were poor quality case series with small numbers of acne-scarred patients. The lack of good quality evidence does not enable any conclusions to be drawn about the effectiveness of lasers for treating atrophic or ice-pick acne scars. Well designed randomised controlled comparisons of carbon dioxide versus Erbium: YAG laser are urgently needed. The aetiology of acne inversa: an evolving story [Ссылки доступны только зарегистрированным пользователям ] ---------------------------------------------------------------- Phenotypic analysis of perennial airborne allergen-specific CD4+ T cells in atopic and non-atopic individuals [Ссылки доступны только зарегистрированным пользователям ] Conclusions and Clinical Relevance Circulating Fel d 1-specific DPB1*0401-restricted CD4+ T cells in both atopic and non-atopic donors maintain a central memory phenotype; however in atopics, the cells had greater Th2 effector function, compatible with a disease model of altered antigen delivery in atopic individuals. Update on the management of chronic eczema: new approaches and emerging treatment options [Ссылки доступны только зарегистрированным пользователям ] Diagnosing chronic hand eczema by an algorithm: a tool for classification in clinical practice [Ссылки доступны только зарегистрированным пользователям ] Filaggrin Mutations are Associated with Recurrent Skin Infection in Singaporean Chinese Patients with Atopic Dermatitis [Ссылки доступны только зарегистрированным пользователям ] Conclusion: This study highlights a novel association between FLG-null mutations and an increased susceptibility to recurrent bacterial skin infection among AD patients. --------------------------------------------------- Stress as an Influencing Factor in Psoriasis [Ссылки доступны только зарегистрированным пользователям ] An extensive number of clinical studies exists supporting stress as an exacerbating factor in psoriasis.[5–12] One problem is that most investigations on stress are generally retrospective, primarily based on patient recall of past events, which may or may not be an entirely reliable measure. However, there are three prospective studies confirming an association between stress and psoriasis.[4,10] In sum, stress appears to be an important precipitating factor in the development and exacerbation of psoriasis. Patients who are identified as stress responders may especially benefit from stress reduction through psychotherapy and/or pharmacotherapy. Onychomycosis in patients with psoriasis – a multicentre study [Ссылки доступны только зарегистрированным пользователям ] An increased prevalence of onychomycosis among the patients with psoriasis was found. Dystrophic nails in psoriasis patients are more predisposed to fungal infections. The mycological examination of all psoriasis patients with nail deformations is considered obligatory because of the great number of psoriasis patients diagnosed with onychomycosis. [Ссылки доступны только зарегистрированным пользователям ] Seasonal variation in vitamin D levels in psoriatic arthritis patients from different latitudes and its association with clinical outcomes Conclusion A high prevalence of vitamin D insufficiency among PsA patients was found. There was no seasonal variation in 25(OH) vitamin D levels among PsA patients in the southern and northern sites. No association could be established between disease activity and vitamin D level. [Ссылки доступны только зарегистрированным пользователям ] Psoriatic arthritis patients lack vitamin D [Ссылки доступны только зарегистрированным пользователям ] Psoriasis patients at increased risk for hospitalization for infectious disease [Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] Conclusion The risk of severe infections was significantly higher for patients with psoriasis compared with control subjects and could not be explained by exposure to systemic antipsoriatic drugs. Optical Coherence Tomography: A New Tool to Assess Nail Disease in Psoriasis? [Ссылки доступны только зарегистрированным пользователям ] Conclusion: OCT has considerable potential for the evaluation of psoriatic nail disease and may be superior to US. Ustekinumab: differential use in psoriasis [Ссылки доступны только зарегистрированным пользователям ] Study on the use of omega-3 fatty acids as a therapeutic supplement in treatment of psoriasis [Ссылки доступны только зарегистрированным пользователям ]
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#52
29.07.2011, 23:17
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Selection of Mycoplasma genitalium strains harbouring macrolide resistance-associated 23S rRNA mutations by treatment with a single 1 g dose of azithromycin
[Ссылки доступны только зарегистрированным пользователям ] Conclusions The single 1 g dose treatment of azithromycin could select M genitalium strains harbouring macrolide resistance-associated mutations. For M genitalium, this regimen might increase the risk of macrolide resistance selection after treatment. Genital and extra-genital warts increase the risk of asymptomatic genital human papillomavirus infection in men [Ссылки доступны только зарегистрированным пользователям ] Conclusions Men with a history of warts on the genitals, fingers, arms and trunk may be at increased risk for acquisition of new genital HPV infections. Warts may provide an efficient reservoir for the transmission of virions to the genitals through auto-inoculation. The potential for the spread of HPV throughout the body through auto-inoculation has important implications for prevention and control of HPV infection. Chlamydia trachomatis infection and risk of cervical intraepithelial neoplasia [Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] Conclusion Further studies based on larger cohorts with longitudinal follow-up in relation to the C trachomatis acquisition and a thorough evaluation of temporal relationships of infections with hrHPV types, C trachomatis and cervical neoplasia are needed to demonstrate whether and how in some situations C trachomatis sets the stage for cervical carcinogenesis. Vulvodynia may be treatable with botulinum toxin injections [Ссылки доступны только зарегистрированным пользователям ] Varicella-zoster virus antigen expression of eccrine gland and duct epithelium in herpes zoster lesions [Ссылки доступны только зарегистрированным пользователям ] Conclusions: Immunohistochemical detection of VZV gE in eccrine epithelium can be a subtle clue to the diagnosis of HZ which displays most unusual manifestations, and VZV-related disorders. ------------------------------------------------------------- A baby with giant freckles? [Ссылки доступны только зарегистрированным пользователям ] The etiology of transient neonatal pustular melanosis remains unclear.1 Gram stains and bacterial cultures from pustular fluid have not revealed a pathogen. The lesions contain neutrophils, sparse eosinophils, keratinous debris, serous fluid, and fragmented hair shafts. A Randomized Controlled Trial of Propranolol for Infantile Hemangiomas[Ссылки доступны только зарегистрированным пользователям ] Conclusion: Propranolol hydrochloride administered orally at 2 mg/kg per day reduced the volume, color, and elevation of focal and segmental IH in infants younger than 6 months and children up to 5 years of age. [Ссылки доступны только зарегистрированным пользователям ] Management of tinea capitis in childhood[Ссылки доступны только зарегистрированным пользователям ] ----------------------------------------------------------------- Handling Botulinum Toxins: An Updated Literature Review [Ссылки доступны только зарегистрированным пользователям ] IncobotulinumtoxinA Gets FDA Okay for Frown Lines [Ссылки доступны только зарегистрированным пользователям ] FDA OKs Xeomin for frown lines [Ссылки доступны только зарегистрированным пользователям ] Objective assessment of skin rejuvenation using near-infrared 1064-nm neodymium: YAG laser in Asians [Ссылки доступны только зарегистрированным пользователям ] Conclusions: NIR irradiation increased elastin in the dermis, and achieved skin rejuvenation. The results indicated that NIR irradiation provides safe and effective long-term stimulation of elastin, which is beneficial for improving dilated pores, skin texture, and wrinkles. Applications of hydroxy acids: classification, mechanisms, and photoactivity [Ссылки доступны только зарегистрированным пользователям ] Interventions for photodamaged skin: a summarised Cochrane review [Ссылки доступны только зарегистрированным пользователям ] Authors’ conclusions There is conclusive evidence that topical tretinoin improves the appearance of mild to moderate photodamage on the face and forearms, in the short-term. However erythema, scaling/dryness, burning/stinging and irritation may be experienced initially. There is limited evidence that tazarotene and isotretinoin benefit patients with moderate photodamage on the face: both are associated with skin irritation and erythema. The effectiveness of other interventions remains uncertain.
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#53
03.08.2011, 13:49
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A systematic literature review of drug therapies for the treatment of psoriatic arthritis: current evidence and meta-analysis informing the EULAR recommendations for the management of psoriatic arthritis.
Ash Z, Gaujoux-Viala C, Gossec L, Hensor EM, Fitzgerald O, Winthrop K, van der Heijde D, Emery P, Smolen JS, Marzo-Ortega H. Source 1Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds, Leeds, UK. Abstract OBJECTIVES: To review the available evidence for the efficacy and safety of non-steroidal anti-inflammatory drugs (NSAIDs), synthetic and biological drug therapies for the different clinical manifestations of psoriatic arthritis (PsA) in order to provide data for the development of treatment recommendations by the European League Against Rheumatism (EULAR) taskforce. METHODS: A systematic literature review (SLR) of available treatments for PsA was performed using the largest electronic databases (MEDLINE, EMBASE and COCHRANE) by two working groups formed within the EULAR taskforce. This comprised a comprehensive sample of rheumatologists, dermatologists, epidemiologists and patients. The available evidence was reviewed for NSAIDs, synthetic disease modifying antirheumatic drugs (DMARDs), local and systemic corticosteroids and biologic drugs. All articles and abstracts published between 1962 and January 2010 were reviewed and considered and a meta-analysis of data on biological therapies was performed. RESULTS: While little data are available on NSAIDs, glucocorticoids and synthetic DMARDs, the available evidence suggests an acceptable efficacy and safety profile of both NSAIDs and synthetic DMARDs (methotrexate, cyclosporine A, sulfasalazine and leflunomide) in PsA. More evidence is available (level 1B) supporting the efficacy of anti-tumour necrosis factor (anti-TNF) agents (adalimumab, etanercept, golimumab and infliximab) in treating the signs and symptoms of PsA as well as reducing radiographic progression. Registry data show no new safety concerns, although the numbers studied to date are relatively small. CONCLUSIONS: This SLR reveals some evidence to support the use of NSAIDs and synthetic DMARDs and good evidence for the efficacy of anti-TNF therapy in PsA. PMID: 21803753 [PubMed - as supplied by publisher]
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#54
12.08.2011, 14:16
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One omalizumab dose improves chronic urticaria
[Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] Conclusion This study demonstrated that a fixed dose of 300 or 600 mg of omalizumab provides rapid and effective treatment of CIU in patients who are symptomatic despite treatment with H1-antihistamines. Peanut allergy: An increasingly common life-threatening disorder [Ссылки доступны только зарегистрированным пользователям ] Pharmacological rationale for the treatment of chronic urticaria with second-generation non-sedating antihistamines at higher-than-standard doses [Ссылки доступны только зарегистрированным пользователям ] Biologics in atopic dermatitis [Ссылки доступны только зарегистрированным пользователям ] In summary, there is a niche for the development of biologics in recalcitrant autoinflammatory stage AD seen mostly in adults. The heterogeneity of patient response to various existing biotherapies points to involvement of various immune responses and may suggest that therapies must preferably target early development of allergen specific B- and T-cell clones. In addition to immune targets, tissular factors that may restore epidermal environment constitute interesting therapeutic tools. Several approaches are needed to find the appropriate targets in a field where so many have been investigated without definitive proof of concept for human systemic therapy in severe disease. The keys to success are probably (1) to influence the inflammatory skin pattern towards less pruritogenic effects, requiring first a better understanding of pruritogenic inflammation and (2) to limit the amplification loop of disease by attacking abnormal regulatory mechanisms which perpetuate skin autoinflammation. Allergic Contact Dermatitis [Ссылки доступны только зарегистрированным пользователям ] Evaluation of the efficacy of methotrexate and cyclosporine therapies on psoriatic nails: a one-blind, randomized study [Ссылки доступны только зарегистрированным пользователям ] Conclusion? Moderate effectiveness on psoriatic nail was found in the two treatment agents and there were no significant differences in efficacy between the groups. A significant improvement was detected in methotrexate group for the nail matrix findings, and in cyclosporine group for the nail bed findings. Combination Therapy of Biologics With Traditional Agents in Psoriasis [Ссылки доступны только зарегистрированным пользователям ] The incidence of leukotrichia in segmental vitiligo: implication of poor response to medical treatment [Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] Conclusions Based on our results, a very high percentage of patients with segmental vitiligo may be associated with leukotrichia. Many white hairs in segmental vitiligo may contribute to the lack of response with medical treatment. The examination of hair color with a digital microscope may be very useful for the prediction of treatment outcome and decision of treatment modalities. Clinical and Dermoscopic Features of 88 Scalp Naevi in 39 Children [Ссылки доступны только зарегистрированным пользователям ] Conclusions Older subjects and boys tend to harbour a larger proportion of scalp naevi. The main clinical patterns include solid-coloured and eclipse naevi. The most common dermoscopic pattern of scalp naevi is the globular pattern. Perifollicular hypopigmentation is a hallmark feature of signature scalp naevi. Dermoscopy is a noninvasive tool in the evaluation of cutaneous melanocytic lesions in children and may decrease the number of unnecessary excisions. Immunotherapy for Cutaneous Malignancy [Ссылки доступны только зарегистрированным пользователям ] CONCLUSIONS Current treatment options for advanced cutaneous malignancies such as melanoma are low in efficacy. Immunotherapies have the potential to provide novel approaches to address this, particularly when used in combination. Conservative surgical management of subungual (matrix derived) melanoma: report of seven cases and literature review [Ссылки доступны только зарегистрированным пользователям ] An improved method of surgical pathology testing for onychomycosis [Ссылки доступны только зарегистрированным пользователям ] Conclusion NaOH pretreatment of nails submitted for a clinical suspicion of onychomycosis is a simple, rapid, and easily adopted method that leads to improved tissue section quality for optimal histopathologic evaluation and diagnosis. Improved tissue sections and adherence to glass slides can reduce the need for repeat sections, thereby reducing costs and preventing delays in turnaround time. Systematic review of nondermatophyte mold onychomycosis: Diagnosis, clinical types, epidemiology, and treatment [Ссылки доступны только зарегистрированным пользователям ] Reticulated Erythema After Nasolabial Fold Injection with Hyaluronic Acid: The Importance of Immediate Attention [Ссылки доступны только зарегистрированным пользователям ] Sexually transmitted infections in pregnant adolescents: prevalence and association with maternal and foetal morbidity [Ссылки доступны только зарегистрированным пользователям ] Conclusions Sexually transmitted infections are frequently asymptomatic and cause maternal–foetal morbidity. The opportunity that pregnancy offers for screening and counselling should not therefore be missed, especially in adolescents. Systemic therapy for primary hyperhidrosis: A*retrospective study of 59 patients treated with glycopyrrolate or clonidine [Ссылки доступны только зарегистрированным пользователям ] Conclusion Systemic therapy with glycopyrrolate or clonidine can be effective for HH. Nearly two-thirds responded to therapy, and less than a quarter had treatment-limiting adverse effects, all of which were self-limited and nonserious. Calciphylaxis: A systematic review of existing and emerging therapies [Ссылки доступны только зарегистрированным пользователям ] Mechanisms of pathological scarring: Role of myofibroblasts and current developments [Ссылки доступны только зарегистрированным пользователям ] The role of the epidermis and the mechanism of action of occlusive dressings in scarring [Ссылки доступны только зарегистрированным пользователям ] The use of noncellularized artificial dermis in the prevention of scar contracture and hypertrophy [Ссылки доступны только зарегистрированным пользователям ] Diffuse and focal palmoplantar keratoderma can be caused by a keratin 6c mutation [Ссылки доступны только зарегистрированным пользователям ] Mild to moderate hidradenitis suppurativa treated with local excision and primary closure [Ссылки доступны только зарегистрированным пользователям ] - уже не первое исследование по применению при гипергидрозе ионофореза/электорофореза, дизайны слабоватые, но исследования постепенно накапливаются; Efficacy of iontophoresis with glycopyrronium bromide for treatment of primary palmar hyperhidrosis [Ссылки доступны только зарегистрированным пользователям ] Conclusions Iontophoresis using glycopyrronium bromide is an effective and well-tolerated treatment for primary palmar hyperhidrosis. The possibility of its greater benefit in patients with more severe baseline disease requires verification. [Ссылки доступны только зарегистрированным пользователям ]
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#55
12.08.2011, 14:51
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- помимо базы pubmed для поиска, в том числе удобно по нужным разделам(дерматология) база trip с rss-лентой, можно просто пользоваться поиском, можно зарегистрироваться, пользоваться только по специальности данными, есть фильтры
[Ссылки доступны только зарегистрированным пользователям ] Cigarette smoking may modify the risk of depression in eczema among adults [Ссылки доступны только зарегистрированным пользователям ] Conclusion Our findings indicated that cigarette smoking may modify the risk of depression in eczema. We suggested cessation of smoking in eczema patients to decrease the risk of this psychiatric co-morbidity. - реакция на Эмлу(о. буллёзный контактный раздражительный дерматит), Case Report Acute bullous irritant contact dermatitis caused by EMLA® cream [Ссылки доступны только зарегистрированным пользователям ] - на бензофенон(химические УФ-фильтры) Multiple contact allergies to benzophenones [Ссылки доступны только зарегистрированным пользователям ] - косметические средства: Two cases of airborne allergic contact dermatitis caused by methylisothiazolinone in paint [Ссылки доступны только зарегистрированным пользователям ] Methylisothiazolinone (MI) in combination with methylchloroisothiazolinone (MCI) is one of the most frequent causes of preservative contact allergy. - анестетик Allergic contact dermatitis caused by tetracaine contained in otic drops [Ссылки доступны только зарегистрированным пользователям ] Contact allergy in the cleaning industry: analysis of contact allergy surveillance data of the Information Network of Departments of Dermatology [Ссылки доступны только зарегистрированным пользователям ] Conclusion. Formaldehyde and rubber additives such as thiurams, zinc diethyldithiocarbamate and mercaptobenzothiazole are occupationally relevant allergens in female cleaners. Prevention strategies are needed to address the problem. Hand eczema in hairdressers: a Danish register-based study of the prevalence of hand eczema and its career consequences [Ссылки доступны только зарегистрированным пользователям ] Conclusions. Hairdressers work an average of 8.4 years in the profession before leaving it, and hand eczema contributes significantly to this career change. Contact allergy and human biomonitoring – an overview with a focus on metals [Ссылки доступны только зарегистрированным пользователям ] A half of schoolchildren with `ISAAC eczema' are ill with allergic contact dermatitis [Ссылки доступны только зарегистрированным пользователям ] Conclusions Our data demonstrate that `ISAAC eczema' is an epidemiological entity that embraces comparable portions of cases of atopic eczema and allergic contact dermatitis, and possibly also other less frequent pruritic dermatoses. Each case of chronic recurrent dermatitis in children requires differential diagnosis aimed at allergic contact dermatitis and inflammatory dermatoses other than atopic eczema, even when predominantly localized in flexural areas. Acquired Cutis Laxa in a 55-year-old Female With Multiple Myeloma and Serologic Evidence of Systemic Lupus Erythematosus [Ссылки доступны только зарегистрированным пользователям ] Possible link between psoriasis and CVD risk factors [Ссылки доступны только зарегистрированным пользователям ] Ustekinumab a Strong Option for Moderate to Severe Psoriasis [Ссылки доступны только зарегистрированным пользователям ] Pregnancy outcomes in women with moderate-to-severe psoriasis [Ссылки доступны только зарегистрированным пользователям ] Conclusion Moderate-to-severe psoriasis is associated with spontaneous and induced abortions, pregnancy-induced hypertensive diseases, premature rupture of membranes, large-for-gestational age newborns, and macrosomia. Conservative surgical management of subungual (matrix derived) melanoma: report of seven cases and literature review [Ссылки доступны только зарегистрированным пользователям ] Conclusions Conservative surgical management in patients with in situ or minimally invasive SUM is a procedure with good cosmetic and functional outcome and, in our cases as well as in the literature, the prognosis is not changed. Combination of Microdermabrasion and 5-Fluorouracil to Induce Repigmentation in Vitiligo: An Observational Study [Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] CONCLUSION Microdermabrasion is adjunctive with topical 5% 5-FU in the treatment of resistant vitiligo patches. Further well-controlled randomized trials are required to validate the observations of the study. Comparison of the epidemiology of acne vulgaris among Caucasian, Asian, Continental Indian and African American women [Ссылки доступны только зарегистрированным пользователям ] Conclusion Acne prevalence and sequelae were more common in those with darker skin types, suggesting that acne is a more heterogeneous condition than previously described and highlight the importance of skin-colour tailored treatment. Evaluation of the Effect of Fractional Laser with Radiofrequency and Fractionated Radiofrequency on the Improvement of Acne Scars [Ссылки доступны только зарегистрированным пользователям ] CONCLUSION This technology may be a useful, nonablative resurfacing treatment for acne scarring. Scarring, texture, and pigmentation improved significantly according to investigator-rated assessment parameters. Although patient satisfaction scores did not improve, overall improvement scores did. Bead-Based Multiplex Genotyping of 58 Cutaneous Human Papillomavirus Types [Ссылки доступны только зарегистрированным пользователям ] In conclusion, McPG is a powerful tool for genotyping of multiple cutaneous HPVs in a high-throughput format and is thus suitable for large-scale epidemiological studies. Multiplex cutaneous Papillomavirus Genotyping (McPG)
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#56
07.10.2011, 23:41
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гомеопатия
- время идет, гомеопатия распространяется(Европа, СНГ, РФ, Москва, Питер...), деньги текут, исследования отслеживаем, "чуда"-ждём, НО все да по одному на выходе:
Homoeopathic remedies in dermatology: a systematic review of controlled clinical trials Conclusions: Reviewed trials of homoeopathic treatments for cutaneous diseases were highly variable in methods and quality. We did not find sufficient evidence from these studies that homoeopathy is clearly efficacious for any single dermatological condition[Ссылки доступны только зарегистрированным пользователям ] Доказательств эффективности нет.
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#57
07.10.2011, 23:55
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микология
- так, исключительно для любопытства, подборка:
POSACONAZOLE (ПОЗАКОНАЗОЛ), аналог - ноксафил [Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] Позаконазол в сравнении с флюконазолом для профилактики грибковой инфекции при тяжелой реакции «трансплантат против хозяина». [Ссылки доступны только зарегистрированным пользователям ] "Позаконазол оказался более эффективным, чем флюконазол в профилактике инвазивного аспергиллеза и в снижении смертности от грибковых инфекций." A Randomised, Placebo- and Active-Controlled, Parallel-Group, Multicentre, Investigator-Blinded Study of Four Treatment Regimens of Posaconazole in Adults With Toenail Onychomycosis [Ссылки доступны только зарегистрированным пользователям ] Conclusion: The efficacy and favourable safety profile of posaconazole suggest a potential new treatment for onychomycosis. The availability of low-cost generic terbinafine may limit posaconazole use to second-line treatment of infections refractory to, or patients intolerant of, terbinafine, or nondermatophyte mould infections. Terbafine spray effectively decontaminates shoes exposed to T. [Ссылки доступны только зарегистрированным пользователям ] A study on the decontamination of insoles colonized by Trichophyton rubrum: effect of terbinafine spray powder 1% and terbinafine spray solution 1% [Ссылки доступны только зарегистрированным пользователям ] Conclusion This study demonstrated the successful treatment of insoles colonized by T. rubrum-infected skin scales. Terbinafine 1% spray solution and powder showed good efficacy; the dermatophyte could no longer be cultured 48*h after a single application of terbinafine. Trichophyton rubrum onychomycosis in an 8-week-old infant[Ссылки доступны только зарегистрированным пользователям ] Onychomycosis is common in adults, uncommon in children and is rare in infants. The most common form of onychomycosis is distal and lateral subungual variant (DLSO) as seen in our case. [2] Distal and lateral subungual onychomycosis is most commonly caused by Trichophyton rubrum. A fungal etiology is unlikely if all fingernails or toenails are dystrophic
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#58
08.10.2011, 00:42
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разное
- текущая ситуация по лепре:
Current status of leprosy: Epidemiology, basic science and clinical perspectives [Ссылки доступны только зарегистрированным пользователям ] Topical permethrin and oral ivermectin in the management of scabies: A prospective, randomized, double blind, controlled study[Ссылки доступны только зарегистрированным пользователям ] Conclusions: Both permethrin and ivermectin in both single and two dose regimen are equally efficacious and well tolerated in scabies. However, permethrin has a rapid onset of action. Multiple lesions of granuloma annulare on the hand in a patient with scabies [Ссылки доступны только зарегистрированным пользователям ] Dermoscopic Features of Skin Lesions in Patients With Mastocytosis[Ссылки доступны только зарегистрированным пользователям ] Reflectance Confocal Microscopic Features of Dermatophytes, Scabies, and Demodex [Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] Dermatoscopy of facial actinic keratosis, intraepidermal carcinoma, and invasive squamous cell carcinoma: A progression model[Ссылки доступны только зарегистрированным пользователям ] Pyoderma gangrenosum, acne, and suppurative hidradenitis (PASH)–a new autoinflammatory syndrome distinct from PAPA syndrome[Ссылки доступны только зарегистрированным пользователям ] Conclusions The clinical triad of pyoderma gangrenosum, acne, and suppurative hidradenitis represents a new disease entity within the spectrum of autoinflammatory syndromes, similar to PAPA and aseptic abscesses syndrome. For this disease, we propose the acronym “PASH” syndrome. PASH syndrome may respond to IL-1? blockade. Infliximab Infusions for Netherton Syndrome: Sustained Clinical Improvement Correlates with a Reduction of Thymic Stromal Lymphopoietin Levels in the Skin [Ссылки доступны только зарегистрированным пользователям ] Neurocutaneous syndrome: A prospective study [Ссылки доступны только зарегистрированным пользователям ] Disorders classified as NCS include neurofibromatosis 1 (NF1), tuberous sclerosis (TS), Sturge-*Weber syndrome*More Details (SWS), von Hippel-Lindau (VHL) disease, PHACE syndrome, ataxia telangiectasia (AT), linear nevus syndrome (LNS), hypomelanosis of Ito (HOI), and incontinentia pigmenti (IP). A clinical study of 125 patients with phrynoderma [Ссылки доступны только зарегистрированным пользователям ] Conclusion: Phrynoderma is a disorder with distinctive clinical features and can be considered as a multifactorial disease involving multiple nutrients, local factors like pressure and friction, and environmental factors in the setting of increased nutritional demand. Phrynoderma, meaning toad skin, is a type of follicular keratosis coined and described by Nocholls in 1933. [1] Various nutritional deficiencies such as Vitamin (Vit) A, Vit B-complex, Vit E and Essential fatty acid (EFA) deficiency, as well as protein-calorie malnutrition have been suggested as possible etiological factors. However, the etiology of the disease is still controversial. The disease was localized (elbows, knees, extensor extremities, and/or buttocks) in 106 (84.8%) patients and generalized (trunk and/or face) in 19 (15.2%) patients. Wickham striae: Etiopathogenensis and clinical significance[Ссылки доступны только зарегистрированным пользователям ] Electrical stimulation boosts therapeutic effect of PDT for keloid scar reduction [Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] German–Austrian–Swiss Consensus Conference on clinical practice in chronic graft-versus-host disease (GVHD): guidance for supportive therapy of chronic cutaneous and musculoskeletal GVHD[Ссылки доступны только зарегистрированным пользователям ] Supportive therapy plays a central role in the management of cutaneous and musculoskeletal manifestations of chronic graft-versus-host disease (cGVHD), either alone or in combination with systemic approaches. What does this study add? - We present results from the German–Austrian–Swiss Consensus Conference on clinical practice in cGVHD, held in Regensburg, Germany, in November 2009. -тThe intention was to achieve a consensus on current evidence-based treatment options as well as to provide guidelines for daily clinical practice.
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#59
08.10.2011, 00:42
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the case report
Genitogluteal porokeratosis involving the scrotum: an unusual presentation of an uncommon disease
[Ссылки доступны только зарегистрированным пользователям ] Giant Schwannoma of the Little Finger [Ссылки доступны только зарегистрированным пользователям ] Progressive symmetric erythrokeratoderma: Report of a Chinese family [Ссылки доступны только зарегистрированным пользователям ] Giant porokeratosis [Ссылки доступны только зарегистрированным пользователям ] Hereditary angioedema: An update [Ссылки доступны только зарегистрированным пользователям ] Epidermoid cyst of penis [Ссылки доступны только зарегистрированным пользователям ] Ultrastructural features of nevus comedonicus [Ссылки доступны только зарегистрированным пользователям ] Oral acanthosis nigricans in chronic hepatitis B with a 21-year follow up [Ссылки доступны только зарегистрированным пользователям ] Persistent pigmented purpuric dermatitis: granulomatous variant [Ссылки доступны только зарегистрированным пользователям ] Coexistence of Two Atypical Variants of Pityriasis Rosea: A Case Report and Review of Literature [Ссылки доступны только зарегистрированным пользователям ]
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#60
08.10.2011, 00:44
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акне
Management of Severe Anogenital Acne Inversa (Hidradenitis Suppurativa)
[Ссылки доступны только зарегистрированным пользователям ] Antibiotics, Acne, and Staphylococcus aureus Colonization [Ссылки доступны только зарегистрированным пользователям ] Conclusion* Unlike current dogma about the long-term use of antimicrobial agents, the prolonged use of tetracycline antibiotics commonly used to treat acne lowered the prevalence of colonization by S aureus and did not increase resistance to the tetracycline antibiotics. Safe and Successful Treatment of Acne Vulgaris with Isotretinoin in a Patient with Chronic Granulomatous Disease [Ссылки доступны только зарегистрированным пользователям ]
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Линейный вид
