Церебральный венозный тромбоз & ЖД анемия

[Dr.Vad]

Церебральный венозный тромбоз у взрослых как осложнение ЖД анемии: (раньше эта патология была описана преимущественно у детей):

Balci K, Utku U, Asil T, Buyukkoyuncu N.
Deep cerebral vein thrombosis associated with iron deficiency anaemia in adults.
J Clin Neurosci. 2007 Feb;14(2):181-4
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Kinoshita Y, Taniura S, Shishido H, Nojima T, Kamitani H, Watanebe T.
Cerebral venous sinus thrombosis associated with iron deficiency: two case reports.
Neurol Med Chir (Tokyo). 2006 Dec;46(12):589-93.
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[Dr.Vad]

Еще немного эвиденса:

J Neurol. 2007 Apr 21;
Anemia as a risk factor for cerebral venous thrombosis? An old hypothesis revisited : Results of a prospective study.
Stolz E,...
Dept. of Neurology, Justus-Liebig-University, Am Steg 14, 35385, Giessen, Germany.

BACKGROUND: Several case reports have linked iron deficiency anemia with the occurrence of cerebral venous thrombosis (CVT) or stroke, yet, it is unclear whether this is a chance association. METHODS: In a case-control design data of whole blood count and screening for thrombophilic coagulation abnormalities of 121 prospectively identified patients with CVT and 120 healthy controls were compared. Anemia was defined as a hemoglobin (Hb) concentration of <120 g/l in females, and <130 g/l in males, severe anemia as a Hb <90 g/l. Adjusted odds ratios (OR) were calculated based on a logistic regression model treating variables with a level of significance of p </= 0.2 on univariate analysis as potential confounders. RESULTS: Thrombophilia (OR 1.22, 95% CI 1.07-1.76, p < 0.01), severe anemia (OR 1.10, 95% CI 1.01-2.22, p < 0.05), and hypercholesterinemia (OR 1.21, 95% CI 1.04-2.57, p < 0.05) were the only independent variables associated with CVT on multivariate analysis. CONCLUSION: Severe anemia is significantly and independently associated with CVT.