|
#11
23.02.2010, 22:10
|
||||
|
||||
|
У пациента-донора тромбоцитов из-за частых процедур (24-26 в год) развился железодефицит, который спровоцировал антероградную амнезию и умеренную депресию по шкале Бека: коррекция железодефицита и снижение интенсивности тромбопцитофереза до 12-13 в год привела к восстановлению памяти и снижению депрессии:
Transfus Med. 2008 Oct;18(5):312-4. Impairment of short-term memory associated with low iron stores in a volunteer multidose plateletpheresis donor. Page EA, Harrison JF, Jaldow EJ, Kopelman M. National Blood Service, Tooting, London, UK. A platelet donor may lose 80-100 mL of blood both in the harness and by blood sampling at each donation, the equivalent of four to five whole blood donations per annum for a donor attending at 2-weekly intervals. A 54-year-old male multidose platelet donor had donated platelets at regular 2-weekly intervals for 6 years. He developed an impairment of anterograde memory (new learning). A self-rating scale revealed a moderate degree of depression [Beck Depression Inventory (BDI) score 22]. Memory testing (Doors and People Memory Battery) showed low scores, particularly for verbal recall and verbal recognition memory. He was found to have a normal haemoglobin of 157 g/L with normal red blood cell indices, but a low serum ferritin (15 ng/mL) and a low serum iron (8.1 mmol/L). Following iron therapy and a return of his iron stores to normal levels, there was an improved BDI score of 13 (minimal level of depression) and a marked improvement in memory test scores. This has been maintained even though he has resumed platelet donation but at reduced intervals. |
|
|
Древовидный вид