Альтернативные методы профилактики герпетических высыпаний на губах

[Dr.Vad]

коррекция железодефицита в течение 3 мес. снизила частоту ежемесячных высыпаний с 0.78 (9-10 в год) до 0.2 (2-3 в год)

Eur J Clin Microbiol Infect Dis. 2000 May;19(5):355-7.
Response to replacement iron therapy in sideropenic individuals with recrudescent herpes labialis.
Willis A, Hyland P, Lamey PJ.
Department of Oral Surgery, Oral Medicine & Oral Pathology, School of Clinical Dentistry, The Queen's University of Belfast, Northern Ireland.

This study investigated the effects of iron replacement on the incidence of recurrent herpes labialis and serum ferritin levels in patients with sideropenia. Ten patients with diagnosed sideropenia and a history of recrudescent herpes labialis were prescribed ferrous sulphate for a period of 3 months. Patients were questioned on the number of episodes of recrudescent herpes labialis that developed per month before treatment and the number of episodes of recrudescent herpes labialis that developed per month after the commencement of replacement iron therapy and during the follow-up period. All blood samples were collected by venipuncture for assay of ferritin levels. Serum ferritin levels were significantly increased compared to pretreatment levels (P<0.05). The number of monthly episodes of recrudescent herpes labialis was reduced from 0.78 to 0.2 episodes per month following treatment (P<0.05). The findings of this study suggest that iron replacement therapy should be further studied as a treatment option in sideropenic individuals with frequent recurrences of recrudescent herpes labialis.
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прием цинка 45 мг в день в течение 2 мес. 2 курса в год снизили высыпания с >6 раз до 3 раз в год:

J Oral Pathol Med. 2005 Aug;34(7):423-5.
Recurrent herpes labialis: a pilot study of the efficacy of zinc therapy.
Femiano F, Gombos F, Scully C.
Stomatology Clinic, II University of Medicines and Surgery, Naples, Italy.

BACKGROUND: The objective of this study was to investigate the effect of zinc on recurrent herpes labialis. MATERIALS/METHODS: Twenty patients (12 females; median age 26.6 years) with a history of recurrent herpes labialis >6 episodes each year were treated with systemic zinc sulphate 22.5 mg twice daily for the months of February, March, September and October. All patients were followed for 12 months. Results: Herpetic lesions reduced to <4 episodes (average 3) for the 12 months and the duration was <7 days for each episode (average 5.7). CONCLUSIONS: Systemic zinc sulphate appeared to reduce both the number of episodes and the time to recovery of herpes labialis.