#16
|
||||
|
||||
|
#17
|
||||
|
||||
Продолжая тему в/в введения поливинилпиролидона...
Очень показательной выглядит публикация (жаль на немецком) о 3 случаях диагностики метастазоподобных образований, вызванных вследствие накопления полимера в клетках РЭС (болезнь накопления ПВП): Pathologe. 2002 Sep;23(5):386-8. [Do polyvinylpyrrolidone (PVP) deposits still occur in internal organs at the turn of the millennium? Observations on three patients from the former USSR] Mohr W, Endres-Klein R. Abteilung Pathologie, Universität Ulm, Albert-Einstein-Allee 11, 89081 Ulm, Germany. PVP had been used as a plasma expander following the end of world war II up to relatively recently but after its intracellular storage became known, it was withdrawn from use. Nevertheless, it was used as a retarding agent for subcutaneous and intramuscular administration of drugs until the 1980s and as a consequence pseudotumors have been observed. Three patients from the former USSR are described with PVP storage in the gastric and duodenal mucosa as well as in lymph nodes. The reason for the administration in these patients and the substances applied remain obscure. It is known that PVP infusions are still performed in Taiwan and that it was also injected intraarticularly as an artificial joint lubricant in Russia in the early 1990s. Because cells with intracytoplasmic deposits of PVP can be misdiagnosed as tumor cells and for reasons of general health - "la maladie polyvinylique" [1] may develop - it is still necessary to retain knowledge of the histology of cellular PVP storage. [Ссылки доступны только зарегистрированным пользователям ] Также в подобном баловстве замечены местечковые шамано-знахари в Тайване и оттуда время от времени публикации: Am J Surg Pathol. 1997 Nov;21(11):1361-7. Cutaneous involvement in polyvinylpyrrolidone storage disease: a clinicopathologic study of five patients, including two patients with severe anemia. Kuo TT, Hu S, Huang CL, Chan HL, Chang MJ, Dunn P, Chen YJ. ---- 'Mucoid dissolution' of bones and multiple pathologic fractures in a patient with past history of intravenous administration of polyvinylpyrrolidone (PVP). A case report. Kepes JJ, Chen WY, Jim YF. Bone Miner. 1993 Jul;22(1):33-41. ---- Localized cutaneous polyvinylpyrrolidone storage disease mimicking cheilitis granulomatosa. Chi CC, Wang SH, Kuo TT. J Cutan Pathol. 2006 Jun;33(6):454-7.
__________________
Искренне, Вадим Валерьевич. |