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#31
15.10.2005, 22:10
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#32
15.10.2005, 22:13
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Цитата:
 A to vu budete prodolzhat' izobretat' velosiped i sil'no rasstroites' kogda vashu dissertatsiu utopyat
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#33
16.10.2005, 14:46
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#34
16.10.2005, 16:56
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#36
16.10.2005, 21:04
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Цитата:
S. Kohro, M. Yamakage, T. Omote and A. Namiki In vitro effects of propofol on blood coagulability and fibrinolysis by the use of thromboelastograph technique. Acta Anaeshthesiol Scand 1999; 43: 217-219 Dogan IV, Ovali E, Eti Z, Yayci A, Gogus FY. The in vitro effects of isoflurane, sevoflurane and propofol on platelet aggregation. Anesth Analg 1999; 88: 432–6 N. L. Law, K. F. J. Ng, M. G. Irwin and J. S. F. Man. Comparison of coagulation and blood loss during anaesthesia with inhaled isoflurane or intravenous propofol. Br J Anaesth 2001; 86: 94–8.
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#37
17.10.2005, 06:37
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You are late!
First two articles are total garbage.Third is cited below for other interested parties
Comparison of coagulation and blood loss during anaesthesia with inhaled isoflurane or intravenous propofol N. L. Law, K. F. J. Ng, M. G. Irwin and J. S. F. Man Department of Anaesthesiology, F Block, Queen Mary Hospital, Pokfulam Road, Hong Kong*Corresponding author Propofol has been reported to affect blood coagulation. This prospective, randomized study compared coagulation and blood loss during anaesthetic maintenance with target-controlled intravenous propofol infusion vs. inhaled isoflurane. Thirty-eight ASA I–III patients undergoing head and neck surgery were allocated randomly to receive either inhaled isoflurane at end-tidal concentration 1–1.5% (group I, n=20) or target-controlled infusion (TCI) of propofol at target concentration 2–5 µg ml–1 (group P, n=18). Thrombelastography® on recalcified whole blood was performed pre-induction, and at 15, 30, 60, 90, 120 min post-induction and 30 min after anaesthesia in both groups. Blood loss was estimated from weighing swabs and the volume in suction bottles. Induced hypotension was not used, and perioperative body temperature was similar between groups. There were no significant differences in thrombelastographic coagulation (R-time, K-time, maximum amplitude and angle) or fibrinolytic variables (lysis index at 30 and 60 min) at all times between groups. Total blood loss was also not significantly different (median group I: 350 ml, range 20–1200 ml; group P: 200 ml, range 50–800 ml). Shortening of R-time and widening of angle developed over time in both groups (P<0.05 groups I and P, repeated measures ANOVA). We conclude that maintenance of anaesthesia with propofol TCI at 2–5 µg ml–1 does not cause detectable coagulation changes on thrombelastography® nor increase surgical blood loss when compared to inhaled isoflurane. Br J Anaesth 2001; 86: 94–8. This is pretty much the end of the story... What else do you want to investigate? What's the phenomenon of erythrocytes aggregation and it's clinical significance??
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#38
18.10.2005, 12:46
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Цитата:
Alessandro Parolari, Daniela Guarnieri, Francesco Alamanni, Thomas Toscano, Vito Tantalo, Tiziano Gherli, Susanna Colli, Fabrizio Foieni, Vincenzo Franzè, Monica Stanghellini, Gian Angelo Gianotti, Paolo Biglioli, and Elena Tremoli Platelet Function and Anesthetics in Cardiac Surgery: An In Vitro and Ex Vivo Study Anesth Analg 1999 89: 26
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