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#31
08.12.2006, 11:34
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от dr.Ira
Цитата:
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#32
08.12.2006, 19:17
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NEONATAL HANDBOOK
[Ссылки доступны только зарегистрированным пользователям ] Abdominal Wall Defects Ambiguous Genitalia Apnoea Bleeding Disorders in the Neonate Blood Gas Interpretation Blood Pressure Bowel Obstruction Breast Feeding Issues Bronchopulmonary Dysplasia Chickenpox (Varicella Zoster) Cleft Lip and Palate Common Limb Problems Congenital Adrenal Hyperplasia Congenital Diaphragmatic Hernia Congenital Infection Cytomegalovirus (CMV) Infection Herpes Simplex Virus Rubella Syphilis Toxoplasmosis Cyanosed Infant Assessment Cytomegalovirus (CMV) Infection Developmental Care Developmental Dysplasia of the Hip Duodenal Atresia Dysmorphology Assessment of the Newborn ELBW Infant - Immediate Management Exchange Transfusion Fetal Hydronephrosis Gastro-oesophageal Reflux GBS Sepsis prevention Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency GroupB Strep Headbox Oxygen Set-up Herpes Simplex Virus Hirschsprung's Disease Hydronephrosis, Fetal Hypocalcaemia Hypoglycaemia Hypokalaemia Hypomagnesaemia Hyponatraemia Hypospadias Hypothyroidism Immunisation of Preterm Infants Incubator to Cot Transfer Infant at risk of neglect and abuse Infant of the Chemically Dependent Woman Infant of the Diabetic Mother (IDM) Inguinal Hernia and Hydrocele Intramuscular (IM) Injection Intraosseous Needle Insertion Intrauterine Infections Intravenous Electrolyte Correction Intravenous Infusion for SCN Admissions Intubation IUGR Infant Jaundice in the first two weeks of life Jejunoileal Atresia Listeria Monocytogenes Infection Meconium Aspiration Syndrome Meconium Ileus Meconium Stained Liquor, Delivery Room Management Meningomyelocele Metabolic acidosis Metabolic Disease a Neonatal Approach Midgut Malrotation and Volvulus Necrotising Enterocolitis Neonatal Abstinence Syndrome Normal Laboratory Values Nutrition of the Preterm Infant Osteopenia of Prematurity Palliative Care Issues Parvovirus Infection Percutaneous Central Venous Catheter Insertion Persistent Pulmonary Hypertension of the Newborn (PPHN) Phototherapy Pneumothorax Drainage Polycythaemia Respiratory Acidosis Respiratory Distress Syndrome (RDS) Resuscitation Retinopathy of Prematurity Rubella SGA Infant Shock Seizures Sepsis Single Umbilical Artery Small for Gestational Age Infants Spina bifida Stridor Supraventricular Tachycardia Surfactant Replacement Therapy Syphilis Thrombocytopenia Thrombosis in Newborns Tiny Baby (<1000g) - Immediate Management</a/> Toxoplasmosis Tracheo-oesophageal fistula and oesophageal atresia Transfer Guidelines Transfusion Tuberculosis (TB) Umbilical Artery Catheterization Umbilcal Cord Care Umbilical Hernias Umbilical Vein Catheterisation Undescended Testes (Crtptorchidism) Vomiting in the Newborn Infant [Ссылки доступны только зарегистрированным пользователям ]
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#33
09.02.2007, 20:46
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[Ссылки доступны только зарегистрированным пользователям ]
Руководство Prevention and management of pain in the neonate: an update. American Academy of Pediatrics [Ссылки доступны только зарегистрированным пользователям ] Evidence-based care guideline for medical management of first urinary tract infection in children 12 years of age or less. Cincinnati Children's Hospital Medical Center [Ссылки доступны только зарегистрированным пользователям ] Postnatal care. Routine postnatal care of women and their babies. National Collaborating Centre for Primary Care
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#34
28.02.2007, 10:33
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Журнал "Оценка медицинских технологий"
полный текст pdf [Ссылки доступны только зарегистрированным пользователям ] Health Technol Assess. 2006 Dec;10(49):iii-iv, ix-xi, 1-157. A systematic review and economic model of the clinical and cost-effectiveness of immunosuppressive therapy for renal transplantation in children. Yao G, Albon E, Adi Y, Milford D, Bayliss S, Ready A, Raftery J, Taylor RS. Health Economics Facility, Health Services Management Centre, University of Birmingham, UK. OBJECTIVES: To review the clinical and cost-effectiveness of basiliximab, daclizumab, tacrolimus, mycophenolate mofetil (MMF), mycophenolate sodium (MPS) and sirolimus as possible immunosuppressive therapies for renal transplantation in children. DATA SOURCES: Electronic databases were searched up to November 2004. REVIEW METHODS: Data from selected studies were extracted and quality assessed. An economic model [Birmingham Sensitivity Analysis paediatrics (BSAp)] was produced based on an adaptation of a model previously developed for the assessment of the cost-effectiveness of immunosuppressants in adults following renal transplant. RESULTS: For the addition of basiliximab, one unpublished paediatric randomised control trial (RCT), reported that the addition of basiliximab to tacrolimus-based triple therapy (BTAS) failed to significantly improve 6-month biopsy-proven acute rejection (BPAR), graft function, graft loss and all-cause mortality. No significant difference between groups was seen in 6-month or 1-year or longer graft loss, all-cause mortality and side-effects. In a meta-analysis of adult RCTs, the addition of basiliximab to a ciclosporin, azathioprine and steroid regimen (CAS) significantly reduced short-term BPAR. There was no significant difference in short- or long-term graft loss, all-cause mortality or side-effects. One adult RCT was included for the addition of daclizumab to CAS, which reported reduced 1-year BPAR, although no difference between groups was seen in either 1- or 3-year graft loss, all-cause mortality and side-effects. For tacrolimus versus ciclosporin, one unpublished paediatric RCT found that a regimen of tacrolimus, azathioprine and a steroid (TAS) reduced 6-month BPAR and improved graft function [glomerular filtration rate (GFR)] compared with CAS. This improvement in BPAR with tacrolimus was as shown in the meta-analysis of adult RCTs. There was evidence, particularly in children, that in comparison with ciclosporin, tacrolimus may reduce long-term graft loss, although there is no benefit on total mortality. The total level of withdrawal in children was reduced in children receiving tacrolimus. Adult RCTs showed an increase in post-transplant diabetes mellitus with tacrolimus. For MMF versus azathioprine, a meta-analysis of adult RCTs showed MMF [regimen of ciclosporin, MMF and a steroid (CMS)] to reduce 1-year BPAR compared with azathioprine (CAS). There was evidence, particularly in children, that in comparison with azathioprine, tacrolimus may reduce long-term graft loss, although there is no benefit on total mortality. There was an increase in the level of cytomegalovirus infection with MMF, although the overall level of withdrawal due to adverse events was not different to that of azathioprine-treated adults. No study comparing MPS with azathioprine (CAS) was identified. In an adult RCT comparing MMF with MPS, there was no significant difference between groups in 1-year efficacy or side-effects. One unpublished paediatric RCT assessed the addition of sirolimus to CAS. BPAR, graft loss and all-cause mortality were not reported. In two adult RCTs, compared with azathioprine, sirolimus reduced 1-year BPAR, reduced graft function (as assessed by an increased serum creatinine) and increased the level of hyperlipidaemia. No significant differences were seen in other efficacy and side-effect outcomes. On an adult RCT comparing sirolimus with ciclosporin, there were no significant differences between groups in 1-year efficacy or side-effects with the exception of an increased level of hyperlipidaemia with sirolimus substitution. Both the assessment group and drug companies assessed the cost-effectiveness of the newer renal immunosuppressants currently licensed in children using an adaptation (BSAp) of the Birmingham Sensitivity Analysis (BSA) model. This model is based on a 10-year extrapolation of 1-year BPAR results sourced from paediatric RCTs or adult RCTs (where paediatric RCTs were not available). The addition of basiliximab and that of daclizumab to CAS was found to increase quality-adjusted life-years (QALYs) and decreased overall costs, a finding that was robust to sensitivity analyses. The incremental cost-effectiveness ratio (ICER) of replacing ciclosporin with tacrolimus was highly sensitive to the selection of the hazard ratio for graft loss from acute rejection, dialysis costs and the incorporation (or not) of side-effects. The ICERs for tacrolimus versus ciclosporin ranged from about 46,000 pounds/QALY to about 146,000 pounds/QALY. Although sensitive to varying the hazard ratio for graft loss with acute rejection, the ICER for replacing azathioprine with MMF remained in excess of 55,000 pounds/QALY. CONCLUSIONS: In general, compared with a regimen of ciclosporin, azathioprine and steroid, the newer immunosuppressive agents consistently reduced the incidence of short-term biopsy-proven acute rejection. However, evidence of the impact on side-effects, long-term graft loss, compliance and overall health-related quality of life is limited. Cost-effectiveness was estimated based on the relationship between short-term acute rejection levels from RCTs and long-term graft loss. Both the addition of daclizumab and that of basiliximab were found to be dominant strategies, that is, regarding cost savings and increased QALYs. The incremental cost-effectiveness of tacrolimus relative to ciclosporin was highly sensitive to key model parameter values and therefore may well be a cost-effective strategy. The incremental cost-effectiveness of MMF compared with azathioprine, although also sensitive to model parameter, was unattractive. There is a particular need for RCTs to assess the use of MMF, MPS and daclizumab for renal transplantation in children where no such evidence currently exists. Future comparative studies need to report not only on the impact of the newer immunosuppressants on short- and long-term clinical outcomes but also on side-effects, compliance, healthcare resource, costs and health-related quality of life.
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#35
08.05.2007, 08:55
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Здоровье подростков
Сollection of the Lancet Series 2007 [Ссылки доступны только зарегистрированным пользователям ]
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#36
27.06.2007, 11:22
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[Ссылки доступны только зарегистрированным пользователям ]
Pediatric Common Questions Quick Answers [Ссылки доступны только зарегистрированным пользователям ] Teen Common Questions Quick Answers
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#37
27.06.2007, 11:25
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[Ссылки доступны только зарегистрированным пользователям ]
GeneralPediatrics.com is the General Pediatrician's View of the Internet Разделы информации для врачей и для пациентов
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#38
27.06.2007, 11:27
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[Ссылки доступны только зарегистрированным пользователям ]
a Pediatric Digital Library and Learning Collaboratory intended to serve as a source of continuing pediatric education
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#39
27.06.2007, 11:29
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Correlapaedia - A Correlative Encyclopedia of Pediatric Imaging, Surgery, and Pathology
[Ссылки доступны только зарегистрированным пользователям ] [Ссылки доступны только зарегистрированным пользователям ] Upper Airway Problems in Children [Ссылки доступны только зарегистрированным пользователям ] Back Pain in Children - A Common Clinical Problem in Children Thoracopaedia: An Imaging Encyclopedia of Pediatric Thoracic Disease [Ссылки доступны только зарегистрированным пользователям ]
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#40
27.06.2007, 11:34
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[Ссылки доступны только зарегистрированным пользователям ]
Virtual Pediatric Patients: A Digital Storytelling System for Teaching Common Pediatric Problems
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#41
28.06.2007, 08:56
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[Ссылки доступны только зарегистрированным пользователям ]
Summaries and commentary of medical journal articles covering a range of topics in pediatrics and adolescent medicine.
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#42
26.08.2007, 16:12
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Новый гайдлайн
Уважаемые коллеги! После многих лет братоубийственных войн наконец
опубликован гайдлайн по инфекциям мочевого тракта у детей. Принимал активное участие в подготовке этого документа - могу выходить на пенсию:bp [Ссылки доступны только зарегистрированным пользователям ]
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#43
22.09.2007, 17:14
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Связанные общей целью: Глобальные усилия по улучшению педиатрической кардиологии - 2007 г.
(Linked by a common purpose: Global efforts for improving pediatric heart health) (на англ.яз) Автор: Благотворительный фонд "Детские сердца" [Children's HeartLink] Описание "...Этот доклад обсуждает факторы, оказывающие влияние на трудности диагностики и лечения врожденных пороков сердца за пределами развитых стран. Он опирается на прошлые исследования заболеваемости и распространенности врожденных и приобретенных пороков сердца у детей, а также освещает тенденции и вопросы привлечения специально подготовленных медсестер и врачей в область педиатрической кардиологии и предотвращения текучести эти кадров. Доклад показывает, что врожденными и приобретенными пороками сердца страдают миллионы детей во всем мире, но большинство из них никогда не получат лечения, в котором они нуждаются....." Как получить Имеется в формате PDF [84 стр.] [Ссылки доступны только зарегистрированным пользователям ].
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#44
01.12.2007, 15:17
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Курс по охране здоровья детей
(The child health care course) 2007 (на англ.яз) Автор: Редактор: Диана Авербук [Diane Awerbuck] Дизайнер: Артур Атвэлл [Arthur Attwell] “Охрана здоровья детей – это одновременно и книга, и курс обучения, разработанный организацией Eduhealthcare. Курс не является локализованным, преподавание которого велось бы в определенном месте и в определенное время; он скорее представляется способом проведения работниками здравоохранения программы самообучения с использованием этой книги в качестве базового текста. В данной новаторской программе вы осуществляете контроль над своим обучением, учитесь решать практические проблемы и выбирать наиболее простые и логичные формы лечения распространенной педиатрический патологии”. Версия 1.0.1 с последними дополнениями, внесенными 23 августа 2007 г., опубликована компанией Electric Book Works Доступна бесплатно в формате PDF [256 стр.] Многовариантные тесты с ответами на них доступны всем, имеющим код курса, а также включены в печатную версию книги, которую можно приобрести в Electric Book Works. [Ссылки доступны только зарегистрированным пользователям ]
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#45
01.12.2007, 15:38
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Санитарное просвещение относительно правильного питания в начальной школе – Руководство по планированию программы обучения
(Nutrition Education in Primary Schools – A Planning Guide for Curriculum Development) (2007) (на англ.яз) Автор: Продовольственная и сельскохозяйственная организация ООН [FAO] Руководство по планированию представляет собой пакет ресурсов, состоящий из трех элементов – подборки учебных текстов, плана мероприятий и программы обучения в классе Имеется в режиме online в виде файлов в формате PDF [Ссылки доступны только зарегистрированным пользователям ]
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Линейный вид
