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Причины анемий
(from Wintrobe's Clinical Hematology)
------------------------------------- Classification of the Normocytic Anemias -------------------------------------------------------------------------- Anemia associated with appropriately increased erythrocyte production Posthemorrhagic anemia Hemolytic anemia Decreased erythropoietin secretion Impaired source >Renal: anemia of renal insufficiency >Hepatic: anemia of liver disease Reduced stimulus (decreased tissue oxygen needs) >Anemia of endocrine deficiency Protein-calorie malnutrition Anemia of chronic disorders Anemia with impaired marrow response Bone marrow hypoplasia Red blood cell aplasia >Acquired pure red cell aplasia in adults >Transient erythroblastopenia of childhood >Transient aplastic crises associated with hemolysis Aplastic anemia (pancytopenia) Bone marrow infiltrative disorders Leukemia Myeloma Other myelophthisic anemias Myelodysplastic anemias Dyserythropoietic anemias (congenital dyserythropoietic anemia type II) Iron deficiency (early) -------------------------------------------------------------------------- -------------------------------------------------------------------------- Classification of Microcytic Anemias -------------------------------------------------------------------------- Disorders of iron metabolism Iron deficiency anemia Anemia of chronic disorders Disorders of globin synthesis Alpha and beta thalassemias Hemoglobin E syndromes (AE, EE, E-beta-thalassemia) Hemoglobin C syndromes (AC, CC) Unstable hemoglobin disease Sideroblastic anemias Hereditary sideroblastic anemia >X-linked >Autosomal Acquired sideroblastic anemia >Refractory anemia with ringed sideroblasts >Malignancies >Myeloproliferative disorders Reversible acquired sideroblastic anemia >Alcoholism >Drugs (isoniazid, chloramphenicol) Lead intoxication (usually normocytic)
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Искренне, Вадим Валерьевич. |
#2
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Common pathologic causes of macrocytosis:
Drugs Alcoholism Reticulocytosis Nonalcoholic and alcoholic liver disease Hypothyroidism Vitamin B12 deficiency Folate deficiency Multiple myeloma Myelodysplastic syndromes Aplastic anemia Acute leukemia
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Искренне, Вадим Валерьевич. |