О пользе рыбьего жира...

[Dr.Vad]

Размещаю сообщение в этом разделе, но может ее переместить в неврологию?

Omega-3 Fatty Acid Supplements May Help Relieve Neck, Low Back Pain

Surg Neurol. 2006;65:326-331

Study Highlights

250 patients were evaluated for nonsurgical spine pain by one neurosurgeon, and the majority had degenerative disc disease with facet arthropathy in the lumbar or cervical spine.

All were taking NSAIDs with 75% on cyclooxygenase-2 inhibitors.

They were asked to take pharmaceutical-grade omega-3 EFAs at a dose of 2.4 g orally daily for 2 weeks then 1.2 g orally daily.

The brand name of the supplement used for the study was not given.
The omega-3 EFA consisted of EPA and DHA.

Participants were asked to taper off their NSAIDs for 1 to 2 weeks after the initial 2 weeks.

There was no placebo group, and participants were not randomized.

One month later, participants were sent a questionnaire about subjective pain, adverse effects, and use of NSAIDs.

Method of statistical analysis was not reported.

Of 250 patients, 125 (50%) returned the questionnaire.

Respondents spent an average of 75 days on fish oil.

Mean age, sex, and other demographics of respondents and nonrespondents were not reported.

78% of respondents were taking 1.2 g, and 22% reported taking 2.4 g of omega-3 EFAs daily.

Actual respondent adherence to supplements was not assessed or reported.

59% of respondents reported discontinuation of NSAID for pain control.

60% of respondents stated that their overall pain was improved vs before starting omega-3 EFAs.

80% of respondents stated that they were satisfied with the improvement in pain.

88% of respondents stated that they would continue to take omega-3 EFA.

There were no significant adverse effects reported by respondents, except for loose bowel movements in 2 respondents.

Potential differences between respondents and nonrespondents in use of omega-3 EFA, pain control, and use of NSAID response were not discussed.

"Our results mirror other controlled studies that compared ibuprofen and omega-3 EFAs demonstrating equivalent effect in reducing arthritic pain," the authors write. "Omega-3 EFA fish oil supplements appear to be a safer alternative to NSAIDs for treatment of nonsurgical neck or back pain in this selective group."

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