[Dr.Anisimova]

Flutamide versus a cyproterone acetate-ethinyl estradiol combination in moderate acne: a pilot randomized clinical trial
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Conclusion: Flutamide appears to be more effective than a cyproterone-estradiol combination in some aspects of acne treatment, but this requires confirmation in a larger trial.
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Management strategies for acne vulgaris
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Retinoid plus antimicrobial combination treatments for acne
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Conclusions: Combination medications have superior efficacy and adherence, and have a similar tolerability profile compared with monotherapy of its components. Several studies have found antibiotic-containing combination products with a retinoid effective for acne. The use of antibiotic-containing combination medications for acne can lead to bacterial resistance. Due to this potential for bacterial resistance, benzoyl peroxide treatments are also recommended in combination with a retinoid.

Rosacea fulminans in pregnancy: successful treatment with azithromycin
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Laser resurfacing for facial acne scars: a summarised cochrane review
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Main results
No randomised controlled trials where laser treatment was compared to either placebo or a different type of laser were found. Most of the 27 studies uncovered were poor quality case series with small numbers of acne-scarred patients.

The lack of good quality evidence does not enable any conclusions to be drawn about the effectiveness of lasers for treating atrophic or ice-pick acne scars. Well designed randomised controlled comparisons of carbon dioxide versus Erbium: YAG laser are urgently needed.

The aetiology of acne inversa: an evolving story
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Phenotypic analysis of perennial airborne allergen-specific CD4+ T cells in atopic and non-atopic individuals
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Conclusions and Clinical Relevance Circulating Fel d 1-specific DPB1*0401-restricted CD4+ T cells in both atopic and non-atopic donors maintain a central memory phenotype; however in atopics, the cells had greater Th2 effector function, compatible with a disease model of altered antigen delivery in atopic individuals.

Update on the management of chronic eczema: new approaches and emerging treatment options
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Diagnosing chronic hand eczema by an algorithm: a tool for classification in clinical practice
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Filaggrin Mutations are Associated with Recurrent Skin Infection in Singaporean Chinese Patients with Atopic Dermatitis
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Conclusion: This study highlights a novel association between FLG-null mutations and an increased susceptibility to recurrent bacterial skin infection among AD patients.
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Stress as an Influencing Factor in Psoriasis
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An extensive number of clinical studies exists supporting stress as an exacerbating factor in psoriasis.[5–12] One problem is that most investigations on stress are generally retrospective, primarily based on patient recall of past events, which may or may not be an entirely reliable measure. However, there are three prospective studies confirming an association between stress and psoriasis.[4,10]
In sum, stress appears to be an important precipitating factor in the development and exacerbation of psoriasis. Patients who are identified as stress responders may especially benefit from stress reduction through psychotherapy and/or pharmacotherapy.

Onychomycosis in patients with psoriasis – a multicentre study
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An increased prevalence of onychomycosis among the patients with psoriasis was found. Dystrophic nails in psoriasis patients are more predisposed to fungal infections. The mycological examination of all psoriasis patients with nail deformations is considered obligatory because of the great number of psoriasis patients diagnosed with onychomycosis.
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Seasonal variation in vitamin D levels in psoriatic arthritis patients from different latitudes and its association with clinical outcomes
Conclusion
A high prevalence of vitamin D insufficiency among PsA patients was found. There was no seasonal variation in 25(OH) vitamin D levels among PsA patients in the southern and northern sites. No association could be established between disease activity and vitamin D level.
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Psoriatic arthritis patients lack vitamin D
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Psoriasis patients at increased risk for hospitalization for infectious disease
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Conclusion
The risk of severe infections was significantly higher for patients with psoriasis compared with control subjects and could not be explained by exposure to systemic antipsoriatic drugs.

Optical Coherence Tomography: A New Tool to Assess Nail Disease in Psoriasis?
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Conclusion: OCT has considerable potential for the evaluation of psoriatic nail disease and may be superior to US.

Ustekinumab: differential use in psoriasis
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Study on the use of omega-3 fatty acids as a therapeutic supplement in treatment of psoriasis
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