[Dr.Anisimova]

Есть смысл именно в наружном интенсивном лечении АД для контроля даже тяжёлых форм(увлажнение и кортикостероиды)
Intensive topical treatment effective for controlling severe pediatric AD
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Conclusion
Intensive inpatient treatment (with wet dressings and topical corticosteroids) was highly effective in controlling severe and recalcitrant atopic dermatitis. Intensive topical treatment, although underused, is an effective first-line approach for patients with severe atopic dermatitis.
Wet dressing therapy in conjunction with topical corticosteroids is effective for rapid control of severe pediatric atopic dermatitis: Experience with 218 patients over 30 years at Mayo Clinic
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Topical fluticasone propionate: intervention and maintenance treatment options of atopic dermatitis based on a high therapeutic index
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- элидел(безопасность) как вторая линия также сохраняет свои позиции, т.е. когда по каким-либо причинам есть смысл вместо кортикостероидов использовать негормональные аналоги, особенно в таких областях как кожа лица, кожа волосистой части головы, складки
- исследования в области безопасности конечно будут еще требовать дальнейшего внимания
Topical calcineurin inhibitors in the treatment of atopic dermatitis – an update on safety issues
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According to current guidelines, TCI are particularly indicated for the treatment of patients suffering from AD, in whom topical CS cannot be employed or treatment duration may be the cause of irreversible side effects. TCI may be thus used advantageously within problem zones, like the face, scalp or intertriginous areas. As for other groups of medications (for example topical CS), treatment with TCI should be managed by experienced specialists and each patient should receive proper education concerning correct use and possible unwanted effects of the therapy. In regards of malignancy risk, there is still a need for long-term or even ultra long-term studies; for the time being, the current indications and age limitations will persist. Furthermore, as long as the results of long-term data are not yet available, effective conventional photoprotection is advised during the topical treatment with pimecrolimus and tacrolimus [16].
Management of AD patient is a complex task, requiring the use of various pharmacological and non-pharmacological measures. Among all of the topical agents used, TCI may be considered as a true breakthrough in conventional therapy of atopic skin. They should not be regarded as a candidate to replace all other medications, but rather as highly valuable, effective safe treatment for the most demanding skin areas involved with atopic inflammation [6].

A study of the correlation between molluscum contagiosum and atopic dermatitis in children.
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Парацетамол
Maternal exposure to acetaminophen, particulate matter increases childhood eczema risk
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the findings of the study suggest that Paracetamol use by mothers in pregnancy is not an independent risk factor for eczema in children, however, even very small doses of Paracetamol taken in pregnancy may contribute to the occurrence of allergic symptoms in early childhood if there is prenatal co-exposure to higher airborne fine particulate matter.

Dead Sea baths effective treatment for severe atopic dermatitis[Ссылки доступны только зарегистрированным пользователям ]
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Conclusion Dead Sea climatotherapy is a particularly effective treatment method for the sub-population of adults with severe AD. The SCORAD 75 can be useful for defining sub-populations in which treatment is more likely to be successful.

Profilaggrin, Dry Skin, and Atopic Dermatitis Risk: Size Matters
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FLG gene, which encodes profilaggrin, are known to be a major risk factor for atopic dermatitis as well as other atopic diseases and systemic allergies. New research, however, shows that intragenic copy number variation within FLG also represents an independent risk factor for atopic dermatitis. The new findings indicate that upregulating FLG protein levels by 5–10% may have clinical utility in improving the management of many patients with dry skin and atopy.