Интересные недавние кейсы-публикации о применении местных бета-блокеров в лечении сосуд. язв:
Topical timolol for a refractory wound.
Tang JC, Dosal J, Kirsner RS.
Dermatol Surg. 2012 Jan;38(1):135-8.
Successful treatment of a chronic venous leg ulcer using a topical beta-blocker.
Lev-Tov H, Dahle S, Moss J, Isseroff RR.
J Am Acad Dermatol. 2013 Oct;69(4):e204-5.
Topical timolol for recalcitrant wounds.
Braun LR, Lamel SA, Richmond NA, Kirsner RS.
JAMA Dermatol. 2013 Dec;149(12):1400-2.
Topical timolol for a chronic ulcer--a case with its own control.
Manahan MN, Peters P, Scuderi S, Surjana D, Beardmore GL.
Med J Aust. 2014 Jan 20;200(1):49-50.
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РКИ похоже в ближ. время не предвидится - из последней публикации: "Timolol has the potential to be an inexpensive, non-invasive and non-labour intensive means to assist wound healing for chronic ulcers. A Phase II trial, looking at the use of topical timolol in ulcers, was halted due to lack of funding..."
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