[Борис Каменецкий]

Далее, два практически одинаковых исследования (разве что поменялся порядок перечисления авторов) с разницей в год на примере 38 и 28 бесплодных пар (привожу текст последнего):
The morphological normalcy of the sperm nucleus and pregnancy rate of intracytoplasmic injection with morphologically selected sperm. Berkovitz A, Eltes F, Yaari S, Katz N, Barr I, Fishman A, Bartoov B. Hum Reprod. 2005 Jan;20(1):185-90. Epub 2004 Oct 7
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Hum Reprod. 2006 Jul;21(7):1787-90. Epub 2006 Feb 23.
Does the presence of nuclear vacuoles in human sperm selected for ICSI affect pregnancy outcome?

Berkovitz A, Eltes F, Ellenbogen A, Peer S, Feldberg D, Bartoov B.
IVF Unit, Department of Obstetrics and Gynaecology, Sapir Medical Center, Meir Hospital, Kfar Saba, and Male Fertility Laboratory, Faculty of Life Sciences, Bar-Ilan University, Ramat Gan, Israel.
BACKGROUND: To verify whether or not microinjection of sperm with a normal nuclear shape but large vacuoles affects IVF-ICSI pregnancy outcome. METHODS: A comparative study testing IVF outcome parameters of IVF-ICSI, based on morphological selection of spermatozoa with normal nuclei against those based on microinjection of sperm with a normal nuclear shape but large vacuoles. An experimental group, including 28 IVF-ICSI cycles, where only embryos obtained from microinjection of spermatozoa with a normal nuclear shape but large vacuoles were transferred, was matched with a control group, including 28 IVF-ICSI cycles, where only embryos obtained from microinjection of spermatozoa with a strictly defined morphologically normal nuclear shape and content were transferred. The main outcome was IVF-ICSI pregnancy rate. RESULTS: The experimental group exhibited a significantly lower pregnancy rate per cycle and significantly higher abortion rate per pregnancy compared to the control group (18 versus 50%, and 80 versus 7%, respectively, P=0.01). CONCLUSION: Microinjection of vacuolated sperm appears to reduce the pregnancy rate and appears to be associated with early abortion.
В исследовании не сравнивается эффективность ИКСИ и ИМСИ. Сравниваются параметры MSOME, как априори достоверные, хотя из предшествующих исследований такого вывода сделать нельзя.