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Старый 01.06.2012, 14:33
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Модный ингредиент БАДов - Коэнзим Ку10. В большинстве БАДов является монокомпонентом, так что доводы про "помойку БАД" не пройдут.

1. Mohr D, Bowry VW, Stocker R (June 1992). "Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation"

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2. Rozen, TD; Oshinsky, ML; Gebeline, CA; Bradley, KC; Young, WB; Shechter, AL; Silberstein, SD (2002). "Open label trial of coenzyme Q10 as a migraine preventive". Cephalalgia 22 (2)

Небольшое исследование

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Цитата:
Mean migraine attack frequency was 4.85 during the baseline period and this decreased to 2.81 attacks by the end of the study period, which was a statistically significant response
3. Alleva R, Tomasetti M, Battino M, Curatola G, Littarru GP, Folkers K (September 1995). "The roles of coenzyme Q10 and vitamin E on the peroxidation of human low density lipoprotein subfractions". Proc. Natl. Acad. Sci. U.S.A. 92 (20): 9388–91

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Ку10 в лечении
Цитата:
These results support the hypothesis that the CoQ10 endowment in subfractions of LDL affects their oxidizability, and they have important implications for the treatment of disease.
4. Sándor, PS; Di Clemente, L; Coppola, G; Saenger, U; Fumal, A; Magis, D; Seidel, L; Agosti, RM et al. (2005). "Efficacy of coenzyme Q10 in migraine prophylaxis: a randomized controlled trial". Neurology 64

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Цитата:
CoQ10 was superior to placebo for attack-frequency, headache-days and days-with-nausea in the third treatment month and well tolerated; 50%-responder-rate for attack frequency was 14.4% for placebo and 47.6% for CoQ10 (number-needed-to-treat: 3). CoQ10 is efficacious and well tolerated.
5. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials.

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Мета-анализ. Доказано, что ку10 эффективен в снижении давления

Цитата:
Meta-analysis was performed in 12 clinical trials (362 patients) comprising three randomized controlled trials, one crossover study and eight open label studies
Цитата:
We conclude that coenzyme Q10 has the potential in hypertensive patients to lower systolic blood pressure by up to 17 mm Hg and diastolic blood pressure by up to 10 mm Hg without significant side effects
6. Quiles, J; Ochoa, JJ; Huertas, JR; Mataix, J (2004). "Coenzyme Q supplementation protects from age-related DNA double-strand breaks and increases lifespan in rats fed on a PUFA-rich diet". Experimental Gerontology 39 (2): 189–94

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Цитата:
These results suggest that a long-term supplementation with a small dosage of coenzyme Q(10) might represent a good anti-aging therapy in rats fed on a PUFA-based diet.
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