Впервые турецкие специалисты показали, что коррекция ЖДА сопровождается улучшением аппетита у детей и повышением количества съедаемых калорий за счет белка и углеводов, что положительно сказывается на наборе веса ребенка:
Iron deficiency anemia was diagnosed by clinic and laboratory findings. All 19 cases were given 5 mg/kg/day iron therapy for 3 months. Results The mean plasma ghrelin level was 936.7±428.8 pg/mL before therapy and it increased to 1284.7±533.3 pg/mL (p<0.001) while the mean plasma leptin level decreased from 3.4±1.6 ng/mL to 1.9±1.0 ng/mL (p<0.01) after therapy. The amount of daily caloric intake, carbohydrate and protein intake were significantly increased after therapy (p<0.001). Δ body weight was correlated with plasma ghrelin levels before and after therapy significantly. In conclusion, the findings of this study indicate that plasma ghrelin level increases and leptin level decreases and growth accelerates because of an increase in appetite and daily calories, carbohydrate and protein amount in children with nutritional iron deficiency anemia after iron therapy.
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J Pediatr Endocrinol Metab. 2019 Feb 23.
The effect of therapy on plasma ghrelin and leptin levels, and appetite in children with iron deficiency anemia.
Kucuk N и соавт.
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