Рылся по терапии упорного рецидивирующего губного герпеса у трехлетки, и нашел про лечебные вакцины инфу.
Делюсь
Цитата:
Therapeutic vaccines
An alternative strategy to augment immune responses and suppress or modulate HSV recurrences is the development of a therapeutic vaccine. Although no randomized clinical trial to date has demonstrated a clear therapeutic benefit, they have provided important insights for future studies. A reduction in recurrences was suggested in response to the Lupidon H and Lupidon G vaccines, which are comprised of whole heat-killed virus from HSV-1 and HSV-2, respectively, although the results were inconclusive due to a lack of appropriate controls and the number of other interventions during the study [48]. A reduction in the number and severity of recurrences was also suggested following immunization with the Skinner vaccine, an inactivated subunit vaccine containing mixed HSV-2 glyco proteins; however, the results were not statistically significant [49]. A disabled infectious single-cycle viral vaccine carrying a deletion of glycoprotein H demonstrated initial promise in animal models [50], but failed to demonstrate protection against recurrences in a Phase II trial [51]. The recombinant glycoprotein vaccine developed by Chriron (MA, USA), gD2gB2-MF59, also did not reduce rates of recurrences or viral shedding, but did reduce symptom and lesion duration [52]. Promising results were more recently obtained in Phase I/II clinical trials with a live-attenuated ICP0 deletion virus, ICP10DPK, which completely prevented recurrences in 37.5 and 43.5% of the vaccinated patients in two trials [53]. Further development and identification of therapeutic vaccine candidates are needed, but mathematical modeling supports the development of a therapeutic HSV vaccine, which could provide both a therapeutic and epidemic-level benefit [54].
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Когда специально искал по запросу на вакцины - не мог найт
Собственно ничего нового не узнал - доказательная база слабая, но можно попробовать от отчаяния иногда. Так маме и сказал.