Of 609 patients younger than 60 years who presented with stroke or TIA, there were 161 abnormalities in hematocrit level or platelet count in 153 patients (25.1%). One hundred sixteen patients had high hematocrit levels (19%), 19 had thrombocytosis (3.1%), 26 had thrombocytopenia (4.3%), and 8 had abnormalities in both lineages (1.3%). A total of 119 patients had repeat testing (74%). Molecular investigations for MPD were warranted in 19 patients (3.1%), performed in 3 patients (.5%) with 2 patients subsequently diagnosed. ADAMTS13 analysis was indicated in 10 patients with thrombocytopenia, performed in 2 patients with 1 diagnosed with TTP thereafter.
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J Stroke Cerebrovasc Dis. 2018 Jul 5. pii: S1052-3057(18)30228-3.
The Importance of the Full Blood Count in Cerebral Ischemia:
A Review of 609 Consecutive Young Patients with Stroke and Transient Ischemic Attacks
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