Вот недавний обзор, где рассматривается влияние диабета на "мужское начало":
Hum Fertil (Camb). 2003 Nov;6(4):174-9.
The hidden impact of diabetes on male sexual dysfunction and fertility.
Glenn DR, McClure N, Lewis SE.
School of Medicine (Ob/Gyn), Queen's University, Institute of Clinical Science, Royal Hospitals, Belfast, N. Ireland, UK.
Diabetes affects an increasingly large number of young men of reproductive age. Erectile and ejaculatory difficulties arise due to vascular and neuropathic problems. The treatment of these may have effects on fertility potential. Erectile dysfunction can be treated with mechanical devices and intracavernosal injections. Although these have not been shown to affect fertility directly, they may result in poor compliance and hence reduced frequency of ejaculation with subsequent deterioration in sperm quality. Other medical treatments may have a more direct effect. The phosphodiesterase (PDE) inhibitor pentoxifylline has been shown to affect sperm quality and early embryo development. Therefore, Viagra, also a PDE inhibitor, may affect sperm quality. There is conflicting evidence about this in the literature. Ejaculatory difficulties are also more common in diabetics although treatments such as Trucut testicular biopsy and intracytoplasmic sperm injection have improved the outlook for these patients. There is also some evidence that spermatogenesis is affected by diabetes and that patients have a reduced sperm motility and semen volume. Therefore, diabetes has a significant impact on the fertility of men with this disease both directly and indirectly. The extent of iatrogenic influence on the reduced fertility potential of these patients needs to be researched as a matter of urgency.
достаточно редко, но иногда причиной и нарушения углеводного обмена и бесплодия может быть гемохроматоз:
Hereditary hemochromatosis (HH) is the most common autosomal recessive disorder in populations of caucasian origin with a prevalence of 1 : 200-400 for homozygous patients. Currently, 4 types of HH are distinguished. The classical and most common form is type 1 hemochromatosis which is characterized by HFE gene mutations on chromosome 6. The disease results from an excessive iron absorption leading to multiple manifestations such as hepatomegaly, diabetes mellitus, cardiomyopathy, infertility, and hepatic fibrosis/cirrhosis if untreated.
Vogt HJ, Weidenbach T, Marquart KH, Vogel GE.
Idiopathic hemochromatosis in a 45-year-old infertile man.
Andrologia. 1987 Sep-Oct;19(5):532-8.
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