Уровень ферритина для исключения железодефицита: 25-30 (или менее 40) мкг/л согласно двум недавним публикациям:
A total of 14 studies were included and were divided into three groups. After the pooled efficacy analysis, we found that the 12 - 20 microg/L group showed the lowest pooled sensitivity (0.767, 95 CI 0.705 -0.821) but highest specificity (0.959, 95 CI 0.934 -0.976). Compared with the other two groups, the pooled sensitivity of 25 - 30 microg/L group (0.877, 95 CI 0.799 - 0.933) was highest, its pooled specificity was (0.944, 95 CI 0.888 - 0.977), the pooled sensitivity and pooled specificity of 36 - 60 microg/L group (0.836, 95 CI 0.797 - 0.870), (0.876, 95 CI 0.846 - 0.901)] were both relatively low. In terms of the integrated diagnostic capabilities, the 25 - 30 microg/L group showed the highest diagnostic odds ratio (101.42, 95 CI 36.137 - 284.64), the largest AUC (0.9497 +/- 0.039) and the Q * index nearest 1 (0.8901 +/- 0.052) among the three groups. After we removed the studies with samples less than 50 and the studies from Chinese authors, the 25 - 30 microg/L group still showed the best diagnostic efficiency.
25 - 30 microg/L of SF as the cut-off value of identifying iron deficiency shows high accuracy and good integrated diagnostic capability.
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Wei Sheng Yan Jiu. 2013 Mar;42(2):228-35.
[Meta-analysis of studies on cut-off value of serum ferritin for identifying iron deficiency].
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Results showed that ferritin can effectively rule out ID anemia in patients with or without inflammatory disease at cut-offs of 70 and 40 μg/L, respectively.
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Clin Chem Lab Med. 2012 Nov;50(11):1911-6.
Revaluating serum ferritin as a marker of body iron stores in the traceability era.
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Искренне,
Вадим Валерьевич.
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