5- The answer is a.
Genetic studies have recently shown that patients with the apolipoprotein E-4 genotype have an increased risk of developing AlzheimerЎЇs disease, posttraumatic encephalopathy
associated with boxing, and worse outcome after traumatic brain injury. Other predictors of a poor outcome are increasing age, lower premorbid level of education, substance abuse history, diffuse axonal injury, subarachnoid hemorrhage, severity of the initial injury, and presence of other systemic injuries. Propofol has been shown in recent studies to improve outcome after injury.
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