A 14-year-old boy is brought to the office by his mother because of "bedwetting" episodes that have been occurring about twice a week for the past few months. The mother says that she noticed this "problem" when she washed his pajamas, and he "refused" to talk about it when she tried to bring it up. She is hoping that he will talk to you. You ask her to leave the room so you can have some privacy with her son. He starts the conversation by stating that "this is getting embarrassing" and he "doesn't understand what's going on." He says that he gets up and finds his pajamas "wet and sticky." He denies any dysuria or frequency during the day, and denies any problems at school or at home. He is on the basketball team, socializes with friends, and gets good grades. Physical examination is unremarkable and shows a pubic hair stage of Tanner IV and genital development Tanner stage III. The next best step is to
A. advise him to stop drinking water at 8 pm and urinate before bed
B. begin a 3-day treatment regimen with trimethoprim-sulfamethoxazole
C. obtain a urine sample for culture and sensitivity
D. order a renal ultrasound
E. reassure him that this is a completely normal part of puberty
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