Уважаемый Александр,
по-моему в Россию PFA-100 еще не завозили, только турбидиметрич. аггрегатометрия доступна, а почему бы и не варфарин?
Еще одно описание повторных стент-тромбозов и обнаруженный дефицит протеина С успешно купирован варфарином:
Int J Cardiovasc Imaging. 2006 Jun-Aug;22(3-4):333-7.
Recurrent acute stent thrombosis associated with protein C and S deficiencies.Acar G, Dogan A, Altinbas A, Turker Y.
Department of Cardiology, Sevket Demirel Heart Center, Suleyman Demirel University, Isparta, Turkey.
Protein C and protein S deficiencies may uncommonly be responsible for coronary arterial thrombosis. We report a young woman with recurrent acute stent thrombosis due to the deficiency of protein C and S. After coronary stenting, stent thrombosis occurred two times despite aggressive antiplatelet therapy, including aspirin, clopidogrel and glycoprotein IIb/IIIa inhibitor. This report suggests that the deficiency of protein C and S should be born in mind in a young patient with recurrent thrombotic events, and that anticoagulants in addition to antiplatelet agents considered in the presence of their deficiency.
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Искренне,
Вадим Валерьевич.
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