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#181
03.01.2018, 00:00
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 ñâÿçè ñ óâåëè÷èâàþùèìñÿ ïîòîêîì áåññîçíàòåëüíîé äåãåëüìåíòèçàöèè íàîáóì ó äåòåé ñî ñëó÷àéíî âûÿâëåííîé ýîçèíîôèëèåé, äîñòóïíûé â ïîëíîé âåðñèè îáçîð ïî äèàãíîñòèêå è âåäåíèþ ïàöèåíòîâ ñ ýîçèíîôèëèåé:
Eosinophilia Due to Allergic Reactions.—Among the reactive eosinophilias in the developed world, allergic reactions are most common, comprising approximately 80% of cases... Eosinophilia Due to Parasitic Infections.—Parasitic infections represent the second most-common cause of eosinophilia in developed nations, comprising 8% of eosinophilias in one large European cohort.5 Generally, the causative organism is a helminth, such as Strongyloides stercoralis. Less often, the culprit may be a single-celled protozoan... The diagnosis of parasitic eosinophilia ultimately requires identification of an infectious trigger, either directly by identifying ova or parasites or indirectly by appropriate serologies, which may vary dependent on travel history... when parasites are implicated, the level of eosinophilia is determined by the extent of tissue invasion, and only tissue parasites are likely to cause clinically important elevations in AEC. Management of allergic eosinophilias involves standard allergen-avoidance measures. In cases of eosinophilia from a drug allergy, the suspected agent should be withheld. Common offenders include allopurinol, carbamazepine, and certain antibiotics.81 However, all medications should be considered, and when there is no clear source, it may become necessary to withhold all nonessential medications. --- Diagnostic Complexities of Eosinophilia [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] 
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#182
29.01.2018, 21:50
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Âñå áîëüøå è áîëüøå ïóáëèêàöèé, ãäå óæå ñ 8-9 ìåñ. âîçðàñòà àíåìèåé ñ÷èòàåòñÿ ãåìîãëîáèí ìåíåå 110 ã/ë, à íå ñ 12 ìåñ. âîçðàñòà:
The present study examined healthy Korean infants (8–15 months old) and their caregivers who visited our clinic for health examinations and ID screening between 2012 and 2015. Cases of ID were defined as infants with 1) serum ferritin levels of < 12 ng/mL or 2) MCV of < 70 fL and transferrin saturation of < 10% (1,27,28). The non-ID group was defined as infants who did not fulfill the ID criteria. Anemia was defined as hemoglobin levels of < 11 g/dL, and IDA was diagnosed based on the coexistence of ID and anemia. [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] çäåñü âîîáùå ñ 6 ìåñ. Iron Nutriture of the Fetus, Neonate, Infant, and Child [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] Ñ Ìåäñêåéïà: ìèíóñ 2ÑÎ ìåíåå 95 ïåðöåíòèëåé èëè óæå àíåìèÿ The reference ranges for hemoglobin concentration in children are as follows: [Ãåìàòîëîãèÿ Õîôìàííà 2009] Birth: mean 16.5 g/dL (-2SD: 13.5 g/dL) 1-3 days: mean 18.5 g/dL (-2SD: 14.5 g/dL) 1 week: mean 17.5 g/dL (-2SD: 13.5 g/dL) 2 weeks: mean 16.5 g/dL (-2SD: 12.5 g/dL) 1 month: mean 14.0 g/dL (-2SD: 10.0 g/dL) 2 months: mean 11.5 g/dL (-2SD: 9.0 g/dL) 3-6 months: mean 11.5 g/dL (-2SD: 9.5 g/dL) 0.5-2 years: mean 12.0 g/dL (-2SD: 11.0 g/dL) 2-6 years: mean 12.5 g/dL (-2SD: 11.5 g/dL) 6-12 years: mean 13.5 g/dL (-2SD: 11.5 g/dL) 12-18 years female: mean 14.0 g/dL (-2SD: 12.0 g/dL) 12-18 years male: mean 14.5 g/dL (-2SD: 13.0 g/dL)
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#184
19.02.2018, 22:25
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Lactose intolerance and gastrointestinal cow’s milk allergy in infants and children – common misconceptions revisited
[Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#185
21.02.2018, 23:39
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Ïðåæäåâðåìåííûå ðîäû è íèçêèé âåñ ïðè ðîæäåíèè ñíèæàþò èíòåëëåêò äåòåé
 èññëåäîâàíèÿõ ïðèíÿëè ó÷àñòèå â îáùåé ñëîæíîñòè 5155 äîíîøåííûõ äåòåé è 7752 ðåáåíêà, ðîäèâøèõñÿ ðàíåå 32-é íåäåëè áåðåìåííîñòè ëèáî âåñèâøèõ ìåíüøå 1500 ãðàììîâ.  âîçðàñòå îò 5 äî 20 ëåò ó÷àñòíèêè ïðîõîäèëè òåñòû íà èíòåëëåêò. Ó÷åíûå óñòàíîâèëè, ÷òî IQ ó äåòåé, ðîäèâøèõñÿ ïðåæäåâðåìåííî, áûë ïðèìåðíî íà 13 ïóíêòîâ íèæå ïî ñðàâíåíèþ ñ òåìè, êòî ðîäèëñÿ â ñðîê. Ñîêðàùåíèå áåðåìåííîñòè íà êàæäóþ íåäåëþ âûëèâàëîñü â ñíèæåíèå IQ íà 1,26 ïóíêòà.
Ñïåöèàëèñòû ñîñòàâèëè ïðîãíîç, îïèðàÿñü íà äàííûå äåòåé ñ ñàìûìè íèçêèìè óðîâíÿìè èíòåëëåêòà. Ïî ïîäñ÷åòàì èññëåäîâàòåëåé, ïðèìåðíî 16% äåòåé, ðîäèâøèõñÿ ðàíüøå âñåãî, áóäóò èìåòü ñåðüåçíûå èíòåëëåêòóàëüíûå íàðóøåíèÿ.  îáùåé ïîïóëÿöèè òàêèå íàðóøåíèÿ ðàçâèâàþòñÿ ïðèìåðíî ó 2,5%. Êðîìå òîãî, ó÷åíûå âûÿñíèëè: ó íåäîíîøåííûõ äåòåé ñ áðîíõîëåãî÷íîé äèñïëàçèåé IQ áûë íèæå, ÷åì ó òåõ, êòî ðîäèëñÿ ïðåæäåâðåìåííî, íî íå ñòðàäàë îò ýòîãî çàáîëåâàíèÿ. JAMA Pediatr. 2018 Feb 19. Cognitive Outcomes of Children Born Extremely or Very Preterm Since the 1990s and Associated Risk Factors: A Meta-analysis and Meta-regression. [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#186
22.02.2018, 20:45
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Íèêîãäà íå ñëûøàë î òàêîì ïðåæäå, ìîæåò è ïåäèàòðàì è äð. ñïåöèàëèñòàì áóäåò èíòåðåñíî - îò àâòîðà àïòóäåéòà:
Food protein-induced enterocolitis syndrome [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] ñàéò è èíôà About Food Protein-Induced Enterocolitis Syndrome [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#187
23.02.2018, 07:37
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Åñëè ó ðåáåíêà îáðàçîâàëñÿ ôèòîáåçîàð, òî â 90% ìîæåò ïîìî÷ü ñïðàâèòñÿ ñ æåëóäî÷íî-êèøå÷íîé íåïðîõîäèìîñòüþ êîêà-êîëà:
Aliment Pharmacol Ther. 2013 Jan;37(2):169-73. Systematic review: Coca-Cola can effectively dissolve gastric phytobezoars as a first-line treatment. [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] +íåäàâíèé îáçîð, ãäå ãîâîðÿò, ÷òî ôèòîáåçîàðû îò ïîåäàíèÿ õóðìû ìîãóò áûòü ðåçèñòåíòíû ê êîêà-êîëå Review of the diagnosis and management of gastrointestinal bezoars [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#188
16.03.2018, 19:06
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Ëåãåíäû è ìèôû âàêöèíàöèè â íåäàâíåé ïóáëèêàöèè:
Wessel L. Vaccine myths. Science. 2017 Apr 28;356(6336):368-372. [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] äîãíàòü è ïåðåãíàòü Àìåðèêó òàêè ïîëó÷èëîñü - ÐÔ è Ôðàíöèÿ â ìèðîâûõ ëèäåðàõ, ãäå ñðåäè íàñåëåíèÿ êàæäûé âòîðîé ùåòàåò, ÷òî âàêöèíû îòòðàâëÿþò æèçíü èõ äåòåé (ðèñ. êàðòû ìèíà íà âòîðîé ñòð. ïî ññûëêå) --- åùå îäíà ïóáëèêàöèÿ ïî ýòîé ïðîáëåìå áóäåò ñâîáîäíî äîñòóïíà ñ èþíÿ 2018: Am Fam Physician. 2017 Jun 15;95(12):786-794. Vaccine Adverse Events: Separating Myth from Reality. Spencer JP è ñîàâò. [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#189
03.04.2018, 18:48
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Íåêîòîðûå èç ïóáëèêàöèé â ïîñëåäíèå ìåñÿöû, ãäå ñèíäðîì âíåçàïíîé ìëàäåí÷åñêîé ñìåðòè àññîöèèðóåòñÿ ñ ìóòàöèÿìè â íàòðèåâûõ êàíàëàõ (skeletal muscle voltage-gated sodium channel, SCN):
Epilepsia. 2018 Apr;59(4):e56-e62. SCN1A variants associated with sudden infant death syndrome. [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] Pacing Clin Electrophysiol. 2018 Mar 23. Multiple genetic variations in sodium channel subunits in a case of Sudden Infant Death Syndrome. [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] ïîëíûé òåêñò â Ëàíöåòå: Dysfunction of NaV1.4, a skeletal muscle voltage-gated sodium channel, in sudden infant death syndrome: a case-control study [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] Ðåä. êîììåíòàðèé Skeletal muscle channelopathy: a new risk for sudden infant death syndrome [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] Î ìåõàíèçìàõ ðàçâèòèÿ áîëåçíåé îò ìóòàöèé â íàòðèåâûõ êàíàëîïàòèÿõ çäåñü Sodium channelopathies of skeletal muscle result from gain or loss of function [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#190
09.04.2018, 19:16
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Äåòè, ïîëó÷àâøèå àíòèáèîòèêè, ïðàçîëû èëè Í2-áëîêàòîðû â ïåðâûå 6 ìåñ. æèçíè ðèñêóþò ïîëó÷èò àëëåðãè÷åñêèå áîëåçíè ê 4-5 ãîäàì - â çàâèñèìîñòè îò äèàãíîçà èõ ðèñê ïîâûøàåòñÿ â 1.5-2.5 ðàçà:
Of 792 130 children (395 215 [49.9%] girls) included for analysis, 60 209 (7.6%) were prescribed an H2RA, 13 687 (1.7%) were prescribed a PPI, and 131 708 (16.6%) were prescribed an antibiotic during the first 6 months of life. Data for each child were available for a median of 4.6 years. Adjusted hazard ratios (aHRs) in children prescribed H2RAs and PPIs, respectively, were 2.18 (95% CI, 2.04-2.33) and 2.59 (95% CI, 2.25-3.00) for food allergy, 1.70 (95% CI, 1.60-1.80) and 1.84 (95% CI, 1.56-2.17) for medication allergy, 1.51 (95% CI, 1.38-1.66) and 1.45 (95% CI, 1.22-1.73) for anaphylaxis, 1.50 (95% CI, 1.46-1.54) and 1.44 (95% CI, 1.36-1.52) for allergic rhinitis, and 1.25 (95% CI, 1.21-1.29) and 1.41 (95% CI, 1.31-1.52) for asthma. The aHRs after antibiotic prescription in the first 6 months of life were 2.09 (95% CI, 2.05-2.13) for asthma, 1.75 (95% CI, 1.72-1.78) for allergic rhinitis, 1.51 (95% CI, 1.38-1.66) for anaphylaxis, and 1.42 (95% CI, 1.34-1.50) for allergic conjunctivitis. --- Association Between Use of Acid-Suppressive Medications and Antibiotics During Infancy and Allergic Diseases in Early Childhood [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#191
21.05.2018, 18:49
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Àóòîèììóííûé ãàñòðèò â ïåäèàòðè÷åñêîé ïðàêòèêå: â áîëüøèíñòâå ñëó÷àåâ ñîïðîâîæäàåòñÿ ðåöèäèâèðóþùåé èëè ðåçèñòåíòíîé ÆÄÀ, äèàãíîç ìîæíî ïîäòâåðäèòü òîëüêî ïðè áèîïñèè ñëèçèñòîé, ïîäðîáíåå:
Autoimmune Gastritis in the Pediatric Age: An Underestimated Condition Report of Two Cases and Review [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#192
13.07.2018, 19:53
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Íåêîòîðûå ïóáëèêàöèè 2017ã. î ïðîêñè-Ìþíõãàóçåíå â ïåäèàòðèè â ïîëíîé âåðñèè èëè òåçèñíî:
Our search yielded a total sample of 796 perpetrators: 309 from case reports and 487 from case series. Information extracted included demographic and clinical characteristics, in addition to methods of abuse and case outcomes. Nearly all abusers were female (97.6%) and the victim’s mother (95.6%). Most were married (75.8%). Mean caretaker age at the child’s presentation was 27.6 years. Perpetrators were frequently reported to be in healthcare-related professions (45.6%), to have had obstetric complications (23.5%), or to have histories of childhood maltreatment (30%). The most common psychiatric diagnoses recorded were factitious disorder imposed on self (30.9%), personality disorder (18.6%), and depression (14.2%). --- The perpetrators of medical child abuse (Munchausen Syndrome by Proxy) – A systematic review of 796 cases [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] ++++++++++++++++ Munchausen by proxy syndrome mimicking systemic autoinflammatory disease: case report and review of the literature [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] ++++++++++++++++ A Serial Munchausen Syndrome by Proxy [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] ++++++++++++++++ Munchausen syndrome and Munchausen syndrome by proxy: a narrative review [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#194
23.07.2018, 21:40
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Ðåäêîå îñëîæíåíèå âàêöèíàöèè - ñèíäðîì Âåëñà (ýîçèíîôèëüíûé öåëëþëèò) êàê ðåàêöèÿ íà íåîìèöèí è àëþìèíèé â ñîñòàâå âàêöèíû:
Pediatr Dermatol. 2018 Jul 12. Pediatric Wells syndrome (eosinophilic cellulitis) after vaccination: A case report and review of the literature. Yu AM è ñîàâò. [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] Ïîäðîáíåå î çàáîëåâàíèè â ïîëíîé âåðñèè ñ êàðòèíêàìè ó âçðîñëûõ è äåòåé: Wells Syndrome in Adults and Children A Report of 19 Cases [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#195
02.08.2018, 22:52
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Íå íîâàÿ èíôîðìàöèÿ, íî íå òåðÿåò àêòóàëüíîñòè è ÷àñòî âñïëûâàåò â ðàáîòå ïåäèàòðà:
How to use the erythrocyte sedimentation rate in paediatrics [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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Ëèíåéíûé âèä
