Цитата:
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Сообщение от V. ZAITSEV
Алексей Викторович!
Что касается сепсиса и озонотерапии, полагаю, достаточно убедительны результаты, немецких исследователей нескольких ин-тов университета Марбурга, Германия, которые, с Ваших слов, и преставления об озонотерапии не имеют.
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Наш ответ про крыс от 1/9/04:
Conclusion 1:
Ozone pretreatment might prevent lethal peritonitis by controlling inflammatory process generated physiologically into the body against specific damage or specific organism.
Conclusions 2:
Ozone pre-treatment was pro-inflammatory in sepsis with a trend to reduced survival. Therefore, its effects in sepsis should be further evaluated in animal trials.
Как быть оппонентам? Кому верить? Может проверим, ну хотя бы еще разочек, ну пожалуйста, перед детским то отделением...
Inflamm Res. 2004 Aug;53 Suppl 2:S122-5. Epub 2004 Aug 10. Related Articles, Links
Pre-treatment with ozonized oxygen (O(3)) aggravates inflammation in septic rats.
Torossian A, Ruehlmann S, Eberhart L, Middeke M, Wulf H, Bauhofer A.
Department of Anaesthesia and Critical Care, University of Marburg, Baldingerstrasse 1, 35033, Marburg, Germany, [
Ссылки доступны только зарегистрированным пользователям ].
Objective and design:Ozone is produced by neutrophils during bacterial killing. Its application was found to be beneficial in peritonitis patients. Therefore, we measured survival and cytokines after ozone pre-treatment in septic rats. Subjects and treatment:With approval, 40 male Wistar-rats were allocated to 1) ozone pre-treatment for five days before intra-abdominal sepsis, or 2) no pre-treatment. Methods:The primary endpoint was mortality at 120 h. Secondary endpoints were plasma cytokine levels. Results:In the control group mortality was 50% (10/20 rats). After ozone pre-treatment, survival was only 35% (7/20 rats, Log-Rank test: P = 0.10). Ozone increased TNF-alpha and MIP-2 after infection: 127+/-23 pg/ml and 94+/-19 pg/ml (control group: 398 pg/ml and 369 pg/ml; P < 0.002 and P < 0.01). IL-6 levels were similar in both groups. Conclusions:
Ozone pre-treatment was pro-inflammatory in sepsis with a trend to reduced survival. Therefore, its effects in sepsis should be further evaluated in animal trials.
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Владимир Яковлевич, увидели полный текст? Нет. Получайте черный шар. За нежелание дать ответ по существу, за очередной повтор, за использование недоказанной методики на беременных и детях и за пустую трату нашего времени.