Экзема/аллергодерматозы, общая дерматология:
- лучше без натрия лаурилсульфата "эмоленты", могут ухудшать течение экземы
Aqueous cream likely to make eczema worse
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"The research has considerable implications for the formulation and labeling of such dermatological products. The action of the detergent sodium lauryl sulphate in aqueous cream is a cause of many of the issues we have identified. Unfortunately the presence of this key ingredient is often not clearly indicated and we would wish to see far more explicit labeling."
Отсроченное введение продуктов(cow's milk, chicken eggs, peanuts, tree nuts, soy, and gluten) для детей(с 6 мес.) не предотвращает аллергозаболевания: крупное исследование, скорее наоборот. Так что принцип "без фанатизма" работает и здесь.
Delaying Intro of Allergenic Foods to Infants Not Suggested
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Conclusion* This study does not support the recommendation for delayed introduction of allergenic foods after age 6 months for the prevention of eczema and wheezing.
- кожная аллергическая реакция может быть не только на то, что снаружи, но и внутри(импланты металлические)
Cutaneous and Systemic Hypersensitivity Reactions to Metallic Implants
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Nickel, cobalt, and chromium are the three most common metals that elicit both cutaneous and extracutaneous allergic reactions from chronic internal exposure. However, other metal ions as well as bone cement components can cause such hypersensitivity reactions. To complicate things, patients may also develop delayed-type hypersensitivity reactions to metals (ie, in-stent restenosis, prosthesis loosening, inflammation, pain, or allergic contact dermatitis) following the insertion of intravascular stents, dental implants, cardiac pacemakers, or implanted gynecologic devices.
- осторожно с нпвс!
Adult purpura fulminans associated with non-steroidal anti-inflammatory drug use
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Purpura fulminans is an acute illness characterized by rapidly progressive dermal vascular thrombosis, leading to hemorrhagic necrosis of the skin. Here, we describe the case of a healthy woman who developed acute disseminated intravascular coagulation (DIC) with purpura fulminans after intramuscular administration of a single dose of ketorolac. Review of literature showed only one case description of non-steroidal anti-inflammatory drug (diclofenac)-related purpura fulminans with DIC.
- "что это" или просто "интересные картинки"
Picture quiz - What links these skin problems?
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Picture quiz - What do these skin problems have in common?
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Picture quiz - what links these dermatological problems?
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Pyogenic granuloma vs amelanotic melanoma
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Clinical picture of the week: Keratocanthoma
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Impetiginised atopic eczema vs eczema herpeticum
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- КПЛ, обращаем внимание на липидный спектр и риск ССС
Chronic inflammation may explain dyslipidemia in lichen planus patients
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Cardiovascular Risk Factors in Patients with Lichen Planus
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Conclusion
Chronic inflammation in patients with lichen planus may explain the association with dyslipidemia. Lipid levels screening in men or women with lichen planus may be useful to detect individuals at risk and start preventive treatment against the development of cardiovascular disease.
Онкология
The impact of gender on the outcome of malignant melanoma: Overview of seven EORTC phase III trials.
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Conclusions: Females exhibit a highly consistent and independent advantage in melanoma progression, metastasis and survival across all stages. Our results suggest a biological tumor-host interaction mechanism to explain this phenomenon, although hormonal status did not seem to explain the female advantage. Unraveling the melanoma gender mystery might reveal new therapeutic possibilities.
Verrucous Carcinoma of the Lip: An Unusual Kissing Type
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Recurrence After Treatment of Nonmelanoma Skin Cancer
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Conclusions* Recurrence of primary NMSC after treatment occurred in less than 5% of tumors. The recurrence rate after ED&C was lower than expected, and the recurrence rate after Mohs surgery was higher than expected. These findings may be related to the risk for recurrence in the treatment groups.
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Melanoma (подробная и простая информация для пациентов и врачей)
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General Information About Melanoma
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Фотозащита: лучше полагаться на одежду(SPF кратно превышает любой крем)
Interest of external photoprotection by means of clothing and sunscreen products in young children
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Conclusion Concerning townwear, the jeans, tracksuits, sweatshirts, pullovers and tights turned out to be very photoprotective. They enable, in effect, to reach a UPF higher than 500. The mere presence of titanium dioxide and/or zinc dioxide does not mean that the product will have a high SPF. Products containing alcohol can be eliminated from the possible choices by carefully reading the label.
Psoriasis and melanocytic naevi: does the first confer a protective role against melanocyte progression to naevi?
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Conclusions People with psoriasis had fewer melanocytic naevi. This suggests that the proinflammatory cytokine network in psoriasis skin might inhibit melanogenesis, melanocyte growth and/or progression to naevi.
Psoriasis pathology may inhibit melanogenesis
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The diagnosis of early psoriatic arthritis in an outpatient dermatological centre for psoriasis
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Conclusions A diagnosis of EPsA can be correctly performed in a dermatologic outpatient facility. To do so, a close collaboration among dermatologists, rheumatologists and radiologists is necessary.
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Survival in cancer patients hospitalized for psoriasis: a population-based cohort study in Sweden
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Conclusions A previous diagnosis of psoriasis worsens the prognosis of many cancers. A worse prognosis was more pronounced in psoriatic cancer patients diagnosed at an earlier age, previously hospitalized for alcohol-related diseases, or with severe symptoms. Our study provides clinicians and patients with information about mortality risk and prognostic factors for psoriatic cancer patients. The mechanisms underlying this disparity warrant further studies.
В некоторых случаях есть смысл назначать системно антимикотики даже при негативном результате диагностики: пресловутый "индивидуальный подход" по-прежнему работает, важно, чтобы безопасно(биохимия)
A rationale for systemic treatment in onychomycosis with negative results on fungal examination
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Conclusions. In the majority of cases of initially negative examinations, consecutive laboratory fungal tests will eventually produce positive results. These findings suggest that systemic antifungal treatment should be started in patients with suspected fungal infections, even if they have negative laboratory fungal examinations.
False_negative_test_results_for_fungal_nail_infect ion_common.html
"Choice of the appropriate treatment should take into account the patient's general health, results of blood tests (complete blood count and liver and renal tests, which should all be normal), current medications, patient preference and which nails are affected," they conclude.
Пока не как стандарт-метод, но потенциально при ацикловир-усточивом герпесе
Topical imiquimod treatment of aciclovir-resistant herpes simplex disease: case series and literature review
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