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Старый 08.10.2011, 01:02
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White piedra of scalp hair by Trichosporon inkin
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Microsporum canis tinea capitis in a centenarian patient
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Eyelash growth in subjects treated with bimatoprost: A multicenter, randomized, double-masked, vehicle-controlled, parallel-group study
[Ссылки доступны только зарегистрированным пользователям ]
Conclusion
Bimatoprost 0.03% was found to be effective at enhancing eyelashes in adults with a very good safety profile.

Androgenetic alopecia as an early marker of benign prostatic hyperplasia[Ссылки доступны только зарегистрированным пользователям ]
Conclusion
There is a relationship between the presence of AGA and prostate growth-associated urinary symptoms, likely attributable to their pathophysiological similarity. This study suggests that early-onset AGA may be an early marker of urinary/prostatic symptomatology. Future studies may clarify whether treatment of patients with AGA may benefit the concomitant benign prostatic hypertrophy, which would be present at an earlier stage in its natural evolution.

A randomized double-blind placebo-controlled pilot study to assess the efficacy of a 24-week topical treatment by latanoprost 0.1% on hair growth and pigmentation in healthy volunteers with androgenetic alopecia[Ссылки доступны только зарегистрированным пользователям ]
Conclusions
Latanoprost significantly increased hair density (terminal and vellus hairs) at 24 weeks compared with baseline and the placebo-treated area. Latanoprost could be useful in stimulating hair follicle activity and treating hair loss.

Demonstration of autoantibodies against tyrosine hydroxylase in patients with alopecia areata
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Conclusion: Antibodies against TH can be present in patients with AA unrelated to APS1. Humoral immune responses against tyrosinase, TRP-1, TRP-2, gp100 and MelanA are not prevalent in AA patients. Overall, a dominant melanocyte-specific B cell autoantigen in AA has yet to be identified.

Kawasaki Disease and Alopecia Areata: Coincidence or a True Association?
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Familial Androgenetic Alopecia in Siblings with Normal Endocrinological Status
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Abstract: Androgenetic alopecia (AGA) is the most common type of hair loss in adults, but it has been rarely reported in children. We report two cases of AGA in two siblings, aged 6 and 8, whose mother had the same condition, without any association with other skin diseases or abnormalities in endocrinologic examinations.

Temporal triangular alopecia: Trichoscopic diagnosis[Ссылки доступны только зарегистрированным пользователям ]
Temporal triangular alopecia (TTA) is circumscribed, non-cicatricial, non-inflammatory hair loss, which is confined to the frontotemporal region.1 TTA is referred to also as congenital triangular alopecia. However, more than half of the cases (55.8%) have been noticed at the age of 2–9*years and only 3.8% in adulthood while 36.5% were found at birth.1 Recently, it has been reported that scalp dermoscopy, also called as trichoscopy,2,3 is useful for diagnosis of TTA without taking biopsy.4 We report here two cases of TTA diagnosed using trichoscopy.
Figure*1. Clinical and trichoscopic appearances of case 1. (a) Temporal hair loss was seen. (b) Trichoscopically normal follicular openings with vellus hairs surrounded by normal terminal hair area was observed.
Because the main clinical feature of TTA is vellus hair and hair follicle miniaturization, which is similar to androgenetic alopecia, we are now considering treatment with topical minoxidil.
Therefore, we propose here the diagnostic criteria for TTA as follows; (i) triangular or lancet-shaped patch of alopecia involving frontotemporal scalp; (ii) trichoscopically normal follicular openings with vellus hairs surrounded by normal terminal hair area; (iii) trichoscopically no broken hairs, tapering hairs, black dots, yellow dots and orifice loss; and (iv) persistent without significant hair regrowth for 6*months after clinically or trichoscopically confirming the existence of vellus hairs.

Utility of dermoscopy in alopecia areata
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Conclusions: The most common dermoscopic finding of AA in our study was yellow dots, followed by black dots, broken hairs, short vellus hair and tapering hairs. Dermoscopic findings were not affected by the type of AA or the severity of the disease.
Dermoscopic findings in alopecia areata
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Prevalence and Etiology of Central Centrifugal Cicatricial Alopecia
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Medical and Environmental Risk Factors for the Development of Central Centrifugal Cicatricial Alopecia
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Conclusions* Our survey results suggest that there is a high prevalence of central hair loss among African American women. Hair styles causing traction as well as inflammation in the form of bacterial infection may be contributing to the development of CCCA. The increase in diabetes mellitus type 2 among those with CCCA is in line with the recent theory that cicatricial alopecia may be a manifestation of metabolic dysregulation.

Human hair follicle: reservoir function and selective targeting
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Penetration of topical compounds may occur via hair follicles.
- The follicular infundibulum increases the surface area and serves as a reservoir.
- Follicular delivery may help to treat localized inflammatory reactions with reduced systemic side-effects, and to develop new strategies in the treatment of scalp diseases.
What does this study add?
- Provides a review on the in vitro and in vivo methods for studying the hair follicle structure, transfollicular penetration pathways and follicular delivery.

The antifungal mechanism of action of zinc pyrithione
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Conclusions The molecular basis for the antifungal activity of the commonly used active ZPT has been elucidated, more than 50*years since its introduction, as utilizing a copper toxicity mechanism that targets critical iron–sulphur proteins.
Little is known of the antifungal mechanism of action of zinc pyrithione (ZPT).
Previous reports indicated that ZPT starves cells for iron and, at high doses, depolarizes membranes.
This study demonstrates for the first time that ZPT inhibits fungal growth through copper import and damage to iron–sulphur proteins.

Improvement In Scalp Hair Growth In Androgen-Deficient Women Treated With Testosterone: A Questionnaire Study
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Conclusions: Subcutaneous testosterone therapy was found to have a beneficial effect on scalp hair growth in female patients treated for symptoms of androgen deficiency. We propose this is due to an anabolic of testosterone on hair growth. The fact that no subject complained of hair loss as a result of treatment casts doubt on the presumed role of testosterone in driving female scalp hair loss. These results need to be confirmed by formal measurements of hair growth.