Identification of a High-Risk Population for Esophageal Injury During Radiofrequency Catheter Ablation of Atrial Fibrillation: Procedural and Anatomical Considerations
Martinek M, Meyer C, Hassanein S, et al.
Heart Rhythm 2010;7:1224-1230.
Study Question: What factors predispose to esophageal injury during radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF)?
Prognostic Value of E/E’ Ratio in Patients With Unoperated Severe Aortic Stenosis
Biner S, Rafique AM, Goykhman P, Morrissey RP, Naghi J, Siegel RJ.
J Am Coll Cardiol Img 2010;3:899-907.
Study Question: Are there clinical or echo/Doppler parameters that have prognostic power among patients with unoperated severe aortic stenosis (AS)?
Analysis of Risk Factors for Abdominal Aortic Aneurysm in a Cohort of More Than 3 Million Individuals
Kent KC, Zwolak RM, Egorova NN, et al.
J Vasc Surg 2010;52:539-548.
Study Question: Who should be screened for abdominal aortic aneurysms (AAAs), and what is the overall prevalence of AAAs in the United States?
Severe Hypoglycemia and Risks of Vascular Events and Death
Zoungas S, Patel A, Chalmers J, et al., on behalf of the ADVANCE Collaborative Group.
N Engl J Med 2010;363:1410-1418.
Study Question: What is the relationship between severe hypoglycemia and adverse clinical outcomes?
Proton-Pump Inhibitors Are Associated With Increased Cardiovascular Risk Independent of Clopidogrel Use: A Nationwide Cohort Study
Charlot M, Ahlehoff O, Norgaard ML et al.
Ann Intern Med 2010;153:378-386.
Study Question: What is the risk for adverse cardiovascular outcomes related to concomitant use of proton pump inhibitors (PPIs) and clopidogrel compared with that of PPIs alone in adults hospitalized for myocardial infarction (MI)?
Clopidogrel With or Without Omeprazole in Coronary Artery Disease
Bhatt DL, Cryer BL, Contant CF, et al., on behalf of the COGENT Investigators.
N Engl J Med 2010;Oct 6:[Epub ahead of print].
Study Question: What is the efficacy and safety of concomitant administration of clopidogrel and proton pump inhibitors (PPIs) in patients with coronary artery disease who are receiving clopidogrel plus aspirin?
Unrecognised Myocardial Infarction and Long-Term Risk of Heart Failure in the Elderly: The Rotterdam Study
Leening MJ, Elias-Smale SE, Felix JF, et al.
Heart 2010;96:1458-1462.
Study Question: What is the long-term risk of heart failure in patients with electrocardiographic (ECG) evidence of unrecognized myocardial infarction (MI)?
Comparison of AngioJet Rheolytic Thrombectomy Before Direct Infarct Artery Stenting With Direct Stenting Alone in Patients With Acute Myocardial Infarction: The JETSTENT Trial
Migliorini A, Stabile A, Rodriguez AE, et al.
J Am Coll Cardiol 2010;56:1298-1306.
Study Question: What is the effect of rheolytic thrombectomy (RT) before direct infarct artery stenting, as compared with direct stenting (DS) on myocardial reperfusion, and clinical outcome in patients with acute myocardial infarction (AMI)?
Prognostic Significance of Myocardial Fibrosis in Hypertrophic Cardiomyopathy
O’Hanlon R, Grasso A, Roughton M, et al.
J Am Coll Cardiol 2010;56:867-874.
Study Question: What is the relationship between myocardial fibrosis detected by late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR) for prediction of clinical events in patients with hypertrophic cardiomyopathy (HCM)?
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