[Dr.Anisimova]

Botulinum Toxin for Glabellar Lines: A Review of the Efficacy and Safety of Currently Available Products
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- очень важно не сочетать воздействие УФ и гликолевых кислот!!!
Synergistic phototoxic effects of glycolic acid in a human keratinocyte cell line (HaCaT)
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Conclusion
We demonstrated that GA, UVB, GA+UVB inhibited proliferation and induced apoptosis in HaCaT cells. The mechanisms of apoptosis induced by co-treatment of GA and UVB involve multiple pathways. The synergistic photo-toxicity may be related to cell cycle arrest and apoptosis in UVB-treated HaCaT cells. These results highlight the potential adverse effects of GA-containing cosmetic agents on human skin.

Skin aging: in*vivo microscopic assessment of epidermal and dermal changes by means of confocal microscopy
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Conclusions
Confocal microscopy was successfully applied to identify in*vivo skin changes occurring in aged skin at both the epidermal and dermal levels at histopathologic resolution. This offers the possibility to test cosmetic product efficacy and to identify early signs of sun damage.

Laser-and-cream combo helps treat melasma in light-skinned patients
Melasma Treatment With Pulsed-Dye Laser and Triple Combination Cream: A Prospective, Randomized, Single-Blind, Split-Face Study
Pulsed-dye laser treatment (PDL) is considered the gold standard therapy for vascular lesions. By targeting not only melanin but also vascularization and at least in part elastosis, PDL might provide, in combination with blanching cream, an effective and complete therapeutic approach for melasma. The objective of this pilot study was to evaluate the dual treatment of fixed triple combination cream (TCC) and PDL in the treatment of melasma.
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Eruptive milium-like syringoma showing eccrine duct origin of milia
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Idiopathic Hemifacial Atrophy Treated with Permanent Polyacrylamide Subdermal Filler
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Hyaluronan and the “Mushroom” Technique: An Assessment of Hyaluronan Injections into the Glans
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An Asian technique of injecting collagen below the corona of the glans—the “mushroom” technique—increases the diameter of the penis glans and heightens sexual sensations for the participant and his sexual partner.

Dysport tops Botox in crow's feet study
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New hydrogel regenerates scar-free tissue
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- олеома- осложнение(правда редкое) мезотерапии целлюлита:
Oleoma: rare complication of mesotherapy for cellulite
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Despite their attraction as purported rejuvenating and “fat-dissolving” injections, the safety and efficacy of these novel cosmetic treatments remain ambiguous, making mesotherapy vulnerable to criticism by the more skeptical medical community. As with any new technology, it is important to assess the benefits, safety, experience, and standardization of mesotherapy. As stated by Atiyeh et*al., “we must be cautious about rejecting new ideas. Just as absence of proof is not proof of absence, lack of scientific validation is not proof that it does not work.”2

A comparison of the efficacy, safety, and longevity of two different hyaluronic acid dermal fillers in the treatment of severe nasolabial folds: a multicenter, prospective, randomized, controlled, single-blind, within-subject study
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a 24 mg/mL smooth gel (Juvederm ULTRA PLUS™ [JUP]) and a 20 mg/mL particulate gel (Perlane® [PER])
Conclusion: These results suggest that different physicochemical properties of HA-based fillers, associated with distinct manufacturing technologies, may influence treatment longevity in the correction of volume deficits. This may relate to a differential resistance to hyaluronidase and/or free radical degradation as previously documented in vitro.

Comparison of Laser Versus Sclerotherapy in the Treatment of Lower Extremity Telangiectases: A Prospective Study
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Lower extremity telangiectases may be equally treated using a Nd:YAG 1,064-nm laser or conventional sclerotherapy. Sclerotherapy is a lower-cost, less-painful method of treatment that will lead to faster clinical improvement, whereas laser is recommended for patients with telangiectatic matting, needle phobia, or allergic reaction to sclerosants.