[Dr.Anisimova]

The Medical Benefits of Male Circumcision
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Granulomas of the penis - a rare complication of intravesical therapy with Bacillus Calmette-Guerin
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Disseminated histoplasmosis mimicking secondary syphilis
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Pigmented plaque-type condyloma acuminatum associated with human papillomavirus type 6
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Генные:
Exacerbation of X-linked ichthyosis phenotype in a female by inheritance of filaggrin and steroid sulfatase mutations
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Conclusion
This is the second reported case of the modifying effects of FLG null alleles on XLI and strengthens the hypothesis that filaggrin defects can synergize with STS deficiency to exacerbate the ichthyosis phenotype.

Prevalence of autosomal recessive congenital ichthyosis: A population-based study using the capture-recapture method in Spain
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Conclusions
The prevalence of ARCI is higher than previously reported. Many patients are not being followed up in reference units, do not have a genetic diagnosis, and are not members of a patient association, indicating room for improvement in their care. Data suggesting a reduced number of older patients might imply a shorter life expectancy and this requires further study.

Микозы:
Majocchi's Granuloma
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A New Classification System for Grading the Severity of Onychomycosis
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Conclusion* The OSI is a new, simple, objective, reproducible numeric system to grade the severity of onychomycosis.
The definition of onychomycosis has been well established; however, there is no
system to evaluate and grade the clinical severity of infection. Most published
reports list poor prognostic factors but do not allow the evaluator to categorize the
nail as mild, moderate, or severe. Using approximately 100 photos of onychomycotic
nails of varying severity, a consensus panel developed a new classification
system based on a several clinical factors to define mild, moderate, and severe
onychomycosis. The scoring model created is similar to the severity index score
used for psoriasis and nail psoriasis and named the Onychomycosis Area Severity
Index Score (OASIS). By defining severity of infection, it may be possible to better
predict the response to therapy and tailor therapy to severity of the disease.
Onychomycosis: A*proposed revision of the clinical classification
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Identification of Ketoconazole as an AhR-Nrf2 Activator in Cultured Human Keratinocytes: The Basis of Its Anti-Inflammatory Effect
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Majocchi's granuloma over the face
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Paracoccidioidomycosis: chronic adult unifocal form
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Role of pH in the pathogenesis of dermatophytoses[Ссылки доступны только зарегистрированным пользователям ]
In this review, we focus on the role of the skin pH in dermatophytosis and the possible mechanisms involved in the adaptive response of dermatophytes to ambient pH changes. Model fungi, in which the pH regulatory system has been extensively characterised, were used as comparative examples.Numerous studies, starting at the end of the nineteenth century, have confirmed the acidic nature of the skin and nail plates.4 The average skin surface and nail plate pH is 4.7, with the skin presenting a pH gradient in which the upper layers are acidic and the pH increases in the deeper layers,5 whereas the pH of the nail plate surface is apparently higher than its interior.6 The skin pH gradient is important for the proper regulation of the activity of enzymes involved in the keratinisation process that is essential for the removal of dead cells and renewal of the stratum corneum, which prevents the colonisation of the skin by harmful microorganisms.4