Да, в такой ситуации можно провести профилактику ацикловиром с 7го по 14й день предполагаемого инкубационного периода, 40-80мг/кг в сутки, разделенные на 4 приема
только нужно знать, что это не рутинная рекомендация
это к какой-то степени экспериментальное лечение
основаны эти рекомендации на довольно скромных доказательствах
вот что пишет аптудейт
Цитата:
ACYCLOVIR FOR POSTEXPOSURE PROPHYLAXIS
Healthy children and adults — Acyclovir is not indicated for routine pre-emptive use among susceptible healthy children, adolescents, or adults after exposure to varicella [ 1 ]. Varicella immunization is preferred for postexposure prophylaxis among healthy susceptible persons. (See 'Types of postexposure prophylaxis' above.)
One small nonrandomized study in 50 Japanese children evaluated the use of acyclovir for the prevention of varicella after household exposure [ 32 ]. The study design compared placebo with acyclovir (40 or 80 mg/kg daily in four divided doses) given on days seven to nine after exposure and continued for seven days [ 32 ]. Varicella developed in fewer of those treated with acyclovir (16 versus 100 percent); the incidence of fever and severity of skin lesions was also reduced in the acyclovir-treated children who did experience infection. However, the conclusions of the study are limited by the small sample size and the design of the study.
There are no randomized studies regarding the use of acyclovir in adults, since this is a less common disease among this age group, even prior to the availability of immunization. Healthy adults who have been exposed to varicella should be immunized with varicella vaccine which is effective in prevention of infection after exposure and affords long-lasting protection.
|