Гиперсегментация нейтрофилов при ЖДА или латентном ЖД наблюдается из-за одновременного пограничного уровня фолиевой, как показала недавляя работа из Ирана:
...correlation between neutrophilic hypersegmentation (NH) and decreased serum iron/ferritin levels ... With logistic regression analysis, it was observed that the relation between NH and ID/IDA is due to concomitant low normal folate levels... The detection of NH in a peripheral blood smear of patients with ID/IDA is a possible reason for a coexistence of mild folate deficiency. It is suggested that in addition to ID/IDA, latent folate deficiency should be investigated in these patients.
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Clin Lab. 2014;60(3):517-22.
The association between neutrophilic hypersegmentation and iron deficiency with regard to folate status in 16-30 year-old women.
Manavifar L, и соавт.
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