Intensive topical treatment effective for controlling severe pediatric AD
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Conclusion
Intensive inpatient treatment (with wet dressings and topical corticosteroids) was highly effective in controlling severe and recalcitrant atopic dermatitis. Intensive topical treatment, although underused, is an effective first-line approach for patients with severe atopic dermatitis.
Second-Generation H1-Antihistamines in Chronic Urticaria: An Evidence-Based Review
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Topical fluticasone propionate: intervention and maintenance treatment options of atopic dermatitis based on a high therapeutic index
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Topical calcineurin inhibitors in the treatment of atopic dermatitis – an update on safety issues
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Wet dressing therapy in conjunction with topical corticosteroids is effective for rapid control of severe pediatric atopic dermatitis: Experience with 218 patients over 30 years at Mayo Clinic
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A study of the correlation between molluscum contagiosum and atopic dermatitis in children.
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Парацетамол
Maternal exposure to acetaminophen, particulate matter increases childhood eczema risk
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the findings of the study suggest that Paracetamol use by mothers in pregnancy is not an independent risk factor for eczema in children, however, even very small doses of Paracetamol taken in pregnancy may contribute to the occurrence of allergic symptoms in early childhood if there is prenatal co-exposure to higher airborne fine particulate matter.
Dead Sea baths effective treatment for severe atopic dermatitis[Ссылки доступны только зарегистрированным пользователям ]
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Conclusion Dead Sea climatotherapy is a particularly effective treatment method for the sub-population of adults with severe AD. The SCORAD 75 can be useful for defining sub-populations in which treatment is more likely to be successful.
Management of chronic spontaneous urticaria in real life – in accordance with the guidelines? A cross-sectional physician-based survey study
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Conclusion The diagnostic and therapeutic management of csU by private practice physicians does not sufficiently comply with the guidelines. Awareness of the guidelines can lead to improved care.
Hypersensitivity reactions to metallic implants – diagnostic algorithm and suggested patch test series for clinical use
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Patch testing is the gold standard for evaluation of type IV hypersensitivity reactions. Appropriate and extensive patch testing is indicated in patients with implanted metal devices and suspected metal hypersensitivity reactions. Although routine pre-implant patch testing is not recommended, there is a subset of individuals with a prior history of reported cutaneous metal hypersensitivity who should be patch tested prior to device implantation. Use of the tables and patient selection algorithms should make the patient selection for testing and allergens that is necessary for thorough evaluation simple and clear. Management following diagnosis of metal hypersensitivity is controversial. There are no objective criteria for determining which patients should undergo additional surgery, with the unavoidable risks and discomforts involved.
There are two final considerations regarding the approach to potentially metal-allergic patients. First, a positive patch test result (an immunological process) is not necessarily relevant to a clinical disease process (allergic contact dermatitis and symptoms such as joint loosening). Do not make management decisions on the basis of a positive test result alone. Second, there are few prospective data available that meet the diagnostic postulates suggested by Thyssen on which to base decisions in these challenging patients (5). Prospective trials are needed to closely examine these patients and provide evidence for an evidence-based approach.
Case report: allergic contact cheilitis caused by ceresin wax
Ceresin is a mineral wax obtained from ozokerite (1). Its structure is similar to that of paraffin, providing a good level of flexibility, adhesiveness, and water resistance. When chlorinated, ceresin is a useful varnish product (1), and it is thus commonly used in floor waxes, textiles, and rubber compounds (2). Although rare, there are reports of occupational dermatoses, particularly among workers using ceresin-containing varnishes (1).
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Occupational contact urticaria caused by polyvinylchloride gloves
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Allergy to natural rubber latex (NRL) gloves in healthcare workers is well recognized, and usually presents as immunological contact urticaria and sometimes anaphylaxis. Latex gloves can also cause allergic contact dermatitis, mostly because of rubber accelerators. As latex sensitivity is well known in healthcare settings, synthetic latex-free gloves are widely used. The most popular latex-free gloves are made of nitrile, polyvinylchloride (PVC), neoprene, or polyethylene. Only a few cases of contact urticaria caused by synthetic rubber or plastic materials have been reported. We describe a case of occupational contact urticaria caused by PVC gloves.
Allergic contact dermatitis caused by a skin-lightening agent, 5,5?-dipropylbiphenyl-2,2?-diol
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Many skin-lightening agents are currently available, including kojic acid, arbutin, hydroquinone, and 5,5?-dipropylbiphenyl-2,2?-diol (Fig. 1); the last of these is a relatively new skin-lightening agent that has been used in Japanese cosmetics since 2006. 5,5?-Dipropylbiphenyl-2,2?-diol is a biphenyl derivative, and downregulates melanin synthesis by inhibiting tyrosinase maturation, leading to accelerated tyrosinase degradation (1). Here, we report a case of allergic contact dermatitis caused by 5,5?-dipropylbiphenyl-2,2?-diol.
Profilaggrin, Dry Skin, and Atopic Dermatitis Risk: Size Matters
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FLG gene, which encodes profilaggrin, are known to be a major risk factor for atopic dermatitis as well as other atopic diseases and systemic allergies. New research, however, shows that intragenic copy number variation within FLG also represents an independent risk factor for atopic dermatitis. The new findings indicate that upregulating FLG protein levels by 5–10% may have clinical utility in improving the management of many patients with dry skin and atopy.
Patch Testing With a Large Series of Metal Allergens
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Conclusion: Many metals not in the standard series were associated with allergic patch-test reactions. The many questions raised by these findings, concerning patch testing with individual metals, will be the subject of future studies.
Efficacy and safety of topical halometasone in eczematous dermatoses in Indian population: An open label, noncomparative study
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Сикортен (Sicorten)
Крем 0,05% по 30 г в тубе, мазь 0,05% по 30 г в тубе
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