[FRSM]

Rising levels of free thyroxine are a risk factor
for a first venous thrombosis. Using data from a
Dutch case-control study on leg vein thrombosis,
researchers estimated risk of venous thrombosis
according to several thresholds of thyroxine
derived from plasma concentrations observed
in controls. In the absence of traditional risk
factors, levels of free thyroxine over 17 pmol/l
yielded a sex and age adjusted odds ratio of
2.2 (95% confidence interval 1.2-4.2) for deep
vein thrombosis (Blood 2010;115:4344-9
doi:10.1182/blood-2009-11-253724).